All AbMole products are for research use only, cannot be used for human consumption.
Curcumin (Diferuloyl), a natural phenolic compound, is a p300/CREB binding protein specific inhibitor that inhibits histone/non-histone acetylation and histone acetyltransferase-dependent chromatin transcription. Curcumin inhibited NF-κ B and MAPKs, and had anti-inflammatory, antioxidant, anti-proliferation and anti-angiogenesis effects. Curcumin induces Nrf2 protein stabilization through Keap1 cysteine modification.
PHYTO medicine. 2024 Apr 03.
Alcohol inducing macrophage M2b polarization in colitis by modulating the TRPV1-MAPK/NF-κB pathways
Curcumin purchased from AbMole
Ann Hematol. 2022 Oct;101(10):2195-2208.
CD277 agonist enhances the immunogenicity of relapsed/refractory acute myeloid leukemia towards Vδ2 + T cell cytotoxicity
Curcumin purchased from AbMole
ACS Appl Mater Interfaces. 2021 Dec 15;13(49):58329-58339.
Ultrashort Peptides and Hyaluronic Acid-Based Injectable Composite Hydrogels for Sustained Drug Release and Chronic Diabetic Wound Healing
Curcumin purchased from AbMole
| Molecular Weight | 368.38 |
| Formula | C21H20O6 |
| CAS Number | 458-37-7 |
| Solubility (25°C) | DMSO 24 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Histone Acetyltransferase Products |
|---|
| CBP/p300-IN-5
P300/CBP-IN-5 is a potent p300/CBP histone acetyltransferase inhibitor, has an IC50 of 18.8 nM. |
| JG-2016
JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1), with an IC50 of 14.8 μM in the HAT1 acetylation assays. |
| AU-18069
AU-18069 is a CBP/p300 HAT inhibitor that can be used in studies related to hematological and solid tumors. |
| KAT modulator-1
KAT modulator-1 is a KAT modulator. |
| KAT6-IN-1
KAT6-IN-1 is a potent KAT6 inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
