Free shipping on all orders over $ 500

Histone Acetyltransferase Histone Acetyltransferase

Cat.No.  Name Information
M3645 MG149 MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF (IC50= 47 uM); little potent for PCAF and p300 (IC50 >200 uM).
M2198 Curcumin Curcumin (Diferuloyl), a natural phenolic compound, is a p300/CREB binding protein specific inhibitor that inhibits histone/non-histone acetylation and histone acetyltransferase-dependent chromatin transcription. Curcumin inhibited NF-κ B and MAPKs, and had anti-inflammatory, antioxidant, anti-proliferation and anti-angiogenesis effects. Curcumin induces Nrf2 protein stabilization through Keap1 cysteine modification.
M55326 JG-2016 JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1), with an IC50 of 14.8 μM in the HAT1 acetylation assays.
M41676 MC4171 MC4171 is a selective KAT8 inhibitor (IC50=8.1 µM).
M40815 PF-9363 PF-9363 is a first-in-class, orally active, highly selective KAT6A/B inhibitor for studies related to ER-positive breast cancer.
M28625 PU139  PU139 is a potent pan-histone acetyltransferase (HAT) inhibitor. PU139 blocks the HATs Gcn5, p300/CBP-associated factor (PCAF), CREB (cAMP response element-binding) protein (CBP) and p300 with IC50s of 8.39, 9.74, 2.49 and 5.35 μM, respectively.
M25562 TTK21 TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 can cross the blood-brain barrier, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has potential for research of brain neurogenesis and long-term memory function.
M25561 CTB CTB is a potent p300 histone acetyltransferase activator. CTB induces time dependence apoptosis of MCF-7 cells.
M13828 CTPB CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme.
M13827 Butyrolactone 3 Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3.
M11175 WM-3835 WM-3835 is a potent, highly specific HBO1 (KAT7 or MYST2) inhibitor that binds directly to the acetyl-Coenzyme A binding site of HBO1 33 and WM-3835 activates apoptosis while inhibiting proliferation, migration, and invasion of osteosarcoma (OS) cells. WM-3835 has anti-tumor activity and effectively inhibits the growth of osteosarcoma xenografts in mice.
M10585 WM-1119 WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with IC50 of 0.25 μM, Kd of 2 nM, WM-1119 is a reversible competitor of acetyl coenzyme A and inhibits MYST-catalysed histone acetylation.
M9919 TH1834 TH1834 is a specific Tip60 (KAT5) histone acetyltransferase (HAT) inhibitor.
M9561 A-485 A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs.
M9469 WM-8014 WM-8014, also known as MOZ-IN-3, is a highly potent inhibitor of MOZ with an IC50 of 55 nM.
M9445 YF2 YF2 is a selective HAT (histone acetyltransferase) activator, with EC50 values of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF and GCN5, respectively.
M9410 Remodelin hydrobromide Remodelin hydrobromide is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
M7738 CPTH2 CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network.
M7065 NU 9056 NU 9056 is a inhibitor of KAT5 (Tip60).
M6808 I-CBP 112 I-CBP 112 is a selective CBP/p300 BRD inhibitor.




Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.