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Cat. No. M13828
CTPB Structure
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5mg USD 330  USD330 4-7 Days
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Quality Control & Documentation
Biological Activity

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme.

Chemical Information
Molecular Weight 554.13
CAS Number 586976-24-1
Solubility (25°C) DMSO 62.5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Oliver Shey-Njila, et al. Int J Mol Sci. CtpB Facilitates Mycobacterium tuberculosis Growth in Copper-Limited Niches

[2] Lei Li, et al. J Cancer Res Ther. Benign pathologies results from lung nodule percutaneous biopsies: How to differentiate true and false benign?

[3] Weidong Chang, et al. Front Plant Sci. Diverged Early From CtpB and CtpC, CtpA Has Evolved to Process D1 Precursor in Oxygenic Photosynthetic Organisms

[4] Andrs Len-Torres, et al. Biol Res. CtpB is a plasma membrane copper (I) transporting P-type ATPase of Mycobacterium tuberculosis

[5] Markus Mastny, et al. Cell. CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis

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Abmole Inhibitor Catalog

Keywords: CTPB supplier, Histone Acetyltransferase, inhibitors, activators

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