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WM-3835 is a potent, highly specific HBO1 (KAT7 or MYST2) inhibitor that binds directly to the acetyl-Coenzyme A binding site of HBO1 33 and WM-3835 activates apoptosis while inhibiting proliferation, migration, and invasion of osteosarcoma (OS) cells.
WM-3835 (10 mg/kg/day; ip; for21 days) potently inhibits pOS-1 xenograft growth in SCID mice.
Molecular Weight | 400.42 |
Formula | C20H17FN2O4S |
CAS Number | 2229025-70-9 |
Solubility (25°C) | DMSO ≥ 120 mg/mL |
Storage | 4°C, protect from light, sealed |
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