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WM-3835

Cat. No. M11175

All AbMole products are for research use only, cannot be used for human consumption.

WM-3835  Structure
Synonym:

WM3835

Size Price Availability Quantity
10mM*1mL in DMSO USD 79  USD79 In stock
1mg USD 32  USD32 In stock
5mg USD 72  USD72 In stock
10mg USD 123  USD123 In stock
25mg USD 244  USD244 In stock
50mg USD 369  USD369 In stock
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Quality Control & Documentation
Biological Activity

WM-3835 is a potent, highly specific HBO1 (KAT7 or MYST2) inhibitor that binds directly to the acetyl-Coenzyme A binding site of HBO1 33 and WM-3835 activates apoptosis while inhibiting proliferation, migration, and invasion of osteosarcoma (OS) cells.

WM-3835 (10 mg/kg/day; ip; for21 days) potently inhibits pOS-1 xenograft growth in SCID mice.

Chemical Information
Molecular Weight 400.42
Formula C20H17FN2O4S
CAS Number 2229025-70-9
Solubility (25°C) DMSO ≥ 120 mg/mL
Storage 4°C, protect from light, sealed
References

[1] Teng-Fei Chen, et al. Int J Biol Sci. HBO1 induces histone acetylation and is important for non-small cell lung cancer cell growth

[2] Jingtian Su, et al. Pharmacol Res. The role of MOZ/KAT6A in hematological malignancies and advances in MOZ/KAT6A inhibitors

[3] Yan-Yang Gao, et al. Theranostics. The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma

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  Catalog
Abmole Inhibitor Catalog




Keywords: WM-3835 , WM3835 supplier, Histone Acetyltransferase, inhibitors, activators

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