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Remodelin hydrobromide is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. Remodelin improves nuclear architecture, chromatin organization, and fitness of both human lamin A/C-depleted cells and HGPS-derived patient cells, and decreases markers of DNA damage in these cells.
| Molecular Weight | 363.28 |
| Formula | C15H15BrN4S |
| CAS Number | 1622921-15-6 |
| Solubility (25°C) | DMSO ≥ 37 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Histone Acetyltransferase Products |
|---|
| CBP/p300-IN-5
P300/CBP-IN-5 is a potent p300/CBP histone acetyltransferase inhibitor, has an IC50 of 18.8 nM. |
| JG-2016
JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1), with an IC50 of 14.8 μM in the HAT1 acetylation assays. |
| AU-18069
AU-18069 is a CBP/p300 HAT inhibitor that can be used in studies related to hematological and solid tumors. |
| KAT modulator-1
KAT modulator-1 is a KAT modulator. |
| KAT6-IN-1
KAT6-IN-1 is a potent KAT6 inhibitor. |
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Products are for research use only. Not for human use. We do not sell to patients.
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