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Artemether

Cat. No. M3378

All AbMole products are for research use only, cannot be used for human consumption.

Artemether Structure
Synonym:

SM-224; CGP 56696; Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether

Size Price Availability Quantity
50mg USD 36 In stock
100mg USD 45 In stock
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Biological Activity

Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria. Artemether has been shown to have significant anticancer and antitumor activities. It is demonstrated that artemether caused strong inhibitory effects on brain glioma growth and angiogenesis in rats. Artemether exhibits a dose- and time-dependent cytotoxicity, and induced apoptosis and G2 cell cycle arrest in ovarian cancer cell lines, human leukemia HL60 cells, and human pancreatic cancer BxPC-3 and AsPC-1 cells.

Chemical Information
Molecular Weight 298.37
Formula C16H26O5
CAS Number 71963-77-4
Solubility (25°C) DMSO 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Charlotte Rasmussen, et al. Continued Low Efficacy of Artemether-Lumefantrine in Angola?

[2] Yaa Boateng-Marfo, et al. Artemether-Loaded Zein Nanoparticles: An Innovative Intravenous Dosage Form for the Management of Severe Malaria

[3] Yujia Li, et al. Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway

[4] Ekpereonne B Esu, et al. Artemether for severe malaria

[5] Ling Wang, et al. P53-dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride-induced liver fibrosis and hepatic stellate cell activation

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Keywords: Artemether, SM-224; CGP 56696; Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether supplier, Antibiotic, inhibitors, activators

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