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Hydroxy Itraconazole

Cat. No. M1587

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Hydroxy Itraconazole Structure
Synonym:

Hydroxy Itraconazole; R-63373

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5mg USD 720  USD720 In stock
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Quality Control & Documentation
Biological Activity

Itraconazole metabolite Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

Chemical Information
Molecular Weight 721.63
Formula C35H38Cl2N8O5
CAS Number 112559-91-8
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nathan P Wiederhold, et al. Variability of Hydroxy-Itraconazole in Relation to Itraconazole Bloodstream Concentrations

[2] Nicole Jenkins, et al. Simultaneous determination of voriconazole, posaconazole, itraconazole and hydroxy-itraconazole in human plasma using LCMS/MS

[3] K De Beule, et al. Pharmacology of itraconazole

[4] J W Hlsewede, et al. Determination of itraconazole and hydroxy-itraconazole in sera using high-performance-liquid-chromatography and a bioassay

[5] R Negroni, et al. Itraconazole: pharmacokinetics and indications

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Keywords: Hydroxy Itraconazole, Hydroxy Itraconazole; R-63373 supplier, Antibiotic, inhibitors, activators

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