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Amphotericin B Solubilized

Cat. No. M1546

All AbMole products are for research use only, cannot be used for human consumption.

Amphotericin B Solubilized Structure
Size Price Availability Quantity
50mg USD 40 In stock
100mg USD 60 In stock
200mg USD 100 In stock
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Quality Control & Documentation
  • Specification: Amphotericin B percentage: ≥6%
  • COA
  • MSDS
Biological Activity

Amphotericin B Solubilized is a powdery form composed of amphotericin sodium deoxycholate and a buffer. This special design enables amphotericin B can be completely dissolved in aqueous solution.

Amphotericin B is a polyene antifungal antibiotic derived from Streptomyces. It has affinity with sterols of fungal cell membranes, especially ergosterol, forming channels on the membrane, making some Small molecule loss.

Antibacterial spectrum: fungi and yeast. Not sensitive to bacteria, rickettsia and viruses.

Chemical Information
Molecular Weight 924.08
Formula C47H73NO17
CAS Number 1397-89-3
Solubility (25°C) Water ≥ 10 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Thi H Yen Tran, et al. Preparation and Characterization of Liposomes Double-loaded with Amphotericin B and Amphotericin B/hydroxypropyl-beta-cyclodextrin Inclusion Complex

[2] Philip Chennell, et al. Do Ophthalmic Solutions of Amphotericin B Solubilised in 2-Hydroxypropyl-γ-Cyclodextrins Possess an Extended Physicochemical Stability?

[3] Dolores R Serrano, et al. Designing Fast-Dissolving Orodispersible Films of Amphotericin B for Oropharyngeal Candidiasis

[4] Dhruv Butani, et al. Amphotericin B topical microemulsion: formulation, characterization and evaluation

[5] D Forster, et al. Toxicity of solubilized and colloidal amphotericin B formulations to human erythrocytes

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