About 32 results found for searched term "SP-B peptide" (0.105 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M51288 | G4RGDSP, integrin-binding peptide | Others |
| G4RGDSP, Integrin-binding peptide is a cell integrin-binding peptide that targets integrin receptors. | ||
| M53521 | SP-B peptide | Antifungal |
| SP-B peptide is an antimicrobial peptide. | ||
| M4918 | Cefuroxime sodium | Antibiotic |
| Cefuroxime sodium salt | ||
| Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase-resistant, bactericidally active, second-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall by inactivating penicillin-binding proteins (PBPs), which interferes with the final transpeptide step required to cross-link the peptidoglycan units, which are the building blocks of the cell wall which ultimately leads to cell lysis. | ||
| M5611 | Embelin | IAP |
| Embelic acid; Emberine; NSC 91874 | ||
| Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties. Specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50 = 4.1 uM in a competitive binding assay with Smac peptide). | ||
| M7137 | Phosphoramidon disodium salt | Neprilysin (NEP) |
| Phosphoramidon disodium salt is a microbial metabolite and an inhibitor of the specific metalloproteases thermolysin, endothelin-converting enzyme (ECE), neutralizing peptidase (NEP) and angiotensin-converting enzyme (ACE), with IC50s of 0.4 μg/mL, 3.5 μM, 0.034 μM and 78 μM, respectively. Phosphoramidon disodium salt also prevented the degradation of amyloid β-peptide and increased Aβ levels in rodents. | ||
| M7866 | Jasplakinolide | Actin-Related Protein |
| Jasplakinolide is an actin-specific reagent that promotes actin polymerization and stabilizes actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity. | ||
| M8432 | CYM50769 | Neuropeptide Receptor |
| CYM50769 is a potent, specific antagonist of the Neuropeptide B and Neuropeptide W receptor, NPBWR1 (IC50 = 120 nM). | ||
| M9857 | TRP-14 | Peptides |
| TRAP; SFLLRNPNDKYEPF; ThroMbin Receptor Agonist Peptide | ||
| Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe is a synthetic thrombin receptor agonist peptide. | ||
| M10884 | YH-53 | Anti-infection |
| YH-53 IS AN EFFECTIVE ONE 3CLpro Inhibitor, 3CL against SARS-CoV-1pro and SARS-CoV-2 3CLpro target Ki The values are 6.3 nM and 34.7 nM, respectively. YH-53 strongly blocks SARS-CoV-2 replication. YH-53 is a peptide-mimetic compound with unique benzothiazolidinone. | ||
| M11406 | Berotralstat | Serine/Threonine Protease |
| Berotralstat (BCX7353) was a second generation plasma kallikrein inhibitor with low toxicity and high specificity, and was used for the diagnosis of hereditary angioedema (HAE). Berotralstat works by blocking the enzyme activity of plasma Kallikrein that releases bradykinin, a major biological peptide that promotes swelling and pain associated with HAE attacks. | ||
| M14663 | Boc-MLF TFA | FPR |
| Boc-Met-Leu-Phe-OH (TFA) | ||
| Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations. | ||
| M19137 | Amoxicillin | Antibiotic |
| Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth. | ||
| M21707 | Recombinant Mouse HSP70 Protein (HEK293, His Tag) | Cytokines and Growth Factors |
| HSPA1A; heat shock 70kDa protein 1A | ||
| HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. The Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. | ||
| M24837 | Tebentafusp | IL Receptor/Related |
| IMCgp100 | ||
| Tebentafusp (IMCgp100) is a bispecific fusion protein to target gp100 peptide-HLA-A*02:01 (a melanoma-associated antigen). Tebentafusp guides T cells to kill gp100-expressing tumor cells via a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain. Tebentafusp leads to inflammatory cytokines and cytolytic proteins production, resulting in the direct lysis of tumour cells. | ||
| M25220 | Sontuzumab | Others |
| AS1402; huHMFG-1 | ||
| Sontuzumab (AS1402) is a humanised IgG1κ MUC1 specific monoclonal antibody. Sontuzumab binds the extracellular MUC1 peptide sequence PDTR with a Kd of ~1 nM. Sontuzumab can be used for the research of breast cancer. | ||
| M28031 | Mipsagargin | Drug-Linker Conjugates for ADC |
| G-202 | ||
| Mipsagargin (G-202) is a novel thapsigargin-based targeted proagent consisting of a prostate-specific membrane antigen (PSMA)-specific peptide coupled to an analog of the potent sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump inhibitor Thapsigargin. Mipsagargin is activated by PSMA-mediated cleavage of an inert masking peptide. Mipsagargin has the potential for refractory, advanced or metastatic solid tumours research. | ||
| M28519 | Pexiganan | Antibiotic |
| MSI 78 free base | ||
| Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections. | ||
| M28632 | CMF019 | Others |
| CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. | ||
| M28905 | Berotralstat dihydrochloride | Serine/Threonine Protease |
| BCX7353 dihydrochloride | ||
| Berotralstat dihydrochloride is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat dihydrochloride works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. | ||
| M28929 | Cyclotriazadisulfonamide | HIV Protease |
| CADA | ||
| Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors. Cyclotriazadisulfonamide (CADA) inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent way. Cyclotriazadisulfonamide is also a Sec61 translocon inhibitor. | ||
| M29523 | SPL-410 | Others |
| SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM. | ||
| M29543 | MS31 | Epigenetic Reader Domain |
| MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells. | ||
| M30408 | Cyclosporin B | Peptides |
| Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation. | ||
| M30588 | Leucinostatin A | Antifungal |
| Antibiotic P168 | ||
| Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies. | ||
| M30649 | C188 | STAT |
| CPD188 | ||
| C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 μM). | ||
| M31013 | MS31 trihydrochloride | Epigenetic Reader Domain |
| MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, and is not toxic to nontumorigenic cells. | ||
| M31380 | Recombinant Human HSP70 Protein (HEK293, N-His) | Cytokines and Growth Factors |
| HSP70-2; HSP72; HSPA1 | ||
| HSP70 can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells. | ||
| M40867 | DSPE-PEG-cRGD | Solvents & Excipients |
| DSPE-PEG-cRGDD is a polymeric material composed of components such as 1,2-didodecyl phosphatidyl lipid (DSPE), polyethylene glycol (PEG), and fibroblast adhesin receptor motif (cRGD). Among them, DSPE is a structurally stable phospholipid, PEG improves the water solubility and stability of polymeric materials, and cRGD is a peptide molecule that plays an important role in the adhesion pathway on the cell surface and has good cell recognition and binding ability. It can be used to prepare nanoparticles for targeting tumors. | ||
| M42869 | Hispidalin | Others |
| Hispidalin is a novel antimicrobial peptide with broad and efficient antibacterial activity against various bacterial and fungal pathogens. | ||
| M43201 | Homoglutathione | Others |
| Homoglutathione is a ubiquitous and indispensable tripeptide in eukaryotes with multi-facetted functions, many of which relate to cellular redox regulation. | ||
| M43267 | CCK1-specific peptide substrate | Others |
| CCK1-specific peptide substrate is a biological active peptide. | ||
| M43271 | beta-Casein phosphopeptide | Others |
| beta-Casein phosphopeptide is a biological active peptide. | ||
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