Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
| Molecular Weight | 365.4 |
| Formula | C16H19N3O5S |
| CAS Number | 26787-78-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 83.33 mg/mL (ultrasonic) Water 2 mg/mL (ultrasonic) |
| Storage | 4°C, protect from light |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Antibiotic Products |
|---|
| TH-Z93
TH-Z93, a lipophilic bisphosphonate, is an FPPS inhibitor (IC50 = 90 nM). TH-Z93 exhibits potent efficacy, increasing both antibody titers and avidity. TH-Z93 exhibited strong prophylactic effects in a pathogenic influenza model. |
| Ningnanmycin
Ningnanmycin is a cytosine nucleoside peptide antibiotic, which is a highly effective, low-toxic, non-accumulative, broad-spectrum fungicide. |
| Sulfacytine
Sulfacytine is a short-acting sulfonamide antibiotic. |
| Cefcapene pivoxil hydrochloride
Cefcapene pivoxil hydrochloride, the pivalate ester precursor form of Cefcapene, is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity. Cefcapene pivoxil hydrochloride has the potential for the palmoplantar pustulosis (PPP) research. |
| Kendomycin
Kendomycin is a polyketide antibiotic with significant antibacterial activity and tumor cytotoxicity. At low concentrations (MIC: 5 μg/mL), Kendomycin inhibits the growth of methicillin-resistant Staphylococcus aureus (MRSA) strain COL. In addition, Kendomycin is an endothelin receptor antagonist and calcitonin receptor agonist. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
