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Tebentafusp (IMCgp100) is a bispecific fusion protein to target gp100 peptide-HLA-A*02:01 (a melanoma-associated antigen). Tebentafusp guides T cells to kill gp100-expressing tumor cells via a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain. Tebentafusp leads to inflammatory cytokines and cytolytic proteins production, resulting in the direct lysis of tumour cells.
| CAS Number | 1874157-95-5 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Sohita Dhillon. Drugs. Tebentafusp: First Approval
[2] Timo E Schank, et al. Future Oncol. Tebentafusp for the treatment of metastatic uveal melanoma
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