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MS31 

Cat. No. M29543

All AbMole products are for research use only, cannot be used for human consumption.

MS31  Structure

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Quality Control & Documentation
Biological Activity

MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells.

Chemical Information
Molecular Weight 341.45
Formula C20H27N3O2
CAS Number 2366264-12-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Pei-Tan Hsueh, et al. Trop Med Infect Dis. Transmission Modes of Melioidosis in Taiwan

[2] E Janet Tawn, et al. J Radiol Prot. Germline minisatellite mutations in workers occupationally exposed to radiation at the Sellafield nuclear facility

[3] A Uzura, et al. J Biosci Bioeng. Involvement of cytochrome P450 in hydroxylation of propylbenzene by Fusarium moniliforme strain MS31

[4] A Uzura, et al. J Biosci Bioeng. Conversion of various aromatic compounds by resting cells of Fusarium moniliforme strain MS31

[5] B Eriksen, et al. Int J Legal Med. DNA polymorphism in Greenland. Allele and profile frequencies in a Greenland population sample using the VNTR probes MS1, MS31, MS43a and YNH24

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  Catalog
Abmole Inhibitor Catalog




Keywords: MS31  supplier, Epigenetic Reader Domain, inhibitors, activators

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