Product Name: | MS31 |
Catalog Number: | M29543 |
CAS Number: | 2366264-12-0 |
Formula: | C20H27N3O2 |
Molecular Weight: | 341.45 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Chemical Structure: | ![]() |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |