About 25 results found for searched term "HIOC" (0.063 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2565 | PR-619 | Deubiquitinase |
| 2,6-Diamino-3,5-dithiocyanopyridine | ||
| PR-619 is a broad-spectrum reversible DUB (deubiquitinating enzyme) inhibitor of USP2, USP4, USP5, USP7 and USP8 with an EC50 of 3-9 μM. PR-619 also induces endoplasmic reticulum stress and endoplasmic reticulum stress-associated apoptosis. | ||
| M1491 | Silver diethyldithiocarbamate | Others |
| Silver diethyldithiocarbamate is used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. | ||
| M4005 | Pyrrolidinedithiocarbamate ammonium (PDTC) | NF-κB |
| Ammonium pyrrolidinedithiocarbamate; APDC | ||
| Pyrrolidinedithiocarbamate ammonium (PDTC) is a selective nuclear factor-κB (NF-κB) inhibitor. | ||
| M4792 | Sinapine-thiocyanate | P-glycoprotein |
| Sinapine, an alkaloid derived from seeds of the cruciferous species, possess antioxidant and radio-protective activities, downregulats multi-drug resistance 1 (MDR1) expression. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor. | ||
| M5745 | Lipoamide | Enzymes & Coenzymes |
| (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide | ||
| Lipoamide is a coenzyme, which transfer acetyl and hydrogen in Pyruvate deacylation oxidation Process, used for pharmaceuticals. | ||
| M5889 | p-Phenylene diisothiocyanate | Parasite |
| 1,4-Diisothiocyanatobenzene; Bitoscanate; PDITC | ||
| p-Phenylene diisothiocyanate is an organic chemical compound used in the treatment of hookworms. | ||
| M6795 | HIOC | Others |
| HIOC is a selective TrkB receptor agonist; neuroprotectant. | ||
| M7752 | Sodium diethyldithiocarbamate trihydrate | NF-κB |
| DIECA | ||
| Sodium diethyldithiocarbamate trihydrate is a chelating agent, generally used in mobilizing toxic metals from the human tissues and experimental animals. Sodium diethyldithiocarbamate trihydrate inhibits induction of macrophage nitric oxide synthase. | ||
| M7951 | Naltrindole isothiocyanate hydrochloride | Others |
| Naltrindole isothiocyanate hydrochloride is a selective irreversible δ2 opioid receptor antagonist. | ||
| M8547 | Thiocolchicoside | Others |
| Thiocolchicoside is a potent competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist with muscle relaxant, anti-inflammatory, and analgesic activity. | ||
| M9156 | Benzyl isothiocyanate | Antibiotic |
| Isothiocyanic Acid Benzyl Ester | ||
| Benzyl isothiocyanate is a naturally-occurring constituent of cruciferous vegetables with antibacterial properties. | ||
| M9157 | 2-Phenylethyl isothiocyanate | Antifungal |
| Isothiocyanic Acid 2-Phenylethyl Ester;2-PE ITC; PEITC | ||
| 2-Phenylethyl isothiocyanate is a natural product found in bean sprouts and cruciferous vegetables, and is also an effective antifungal agent, significantly inhibiting spore germination and mycelial growth of Aspergillus intermedius. In addition, 2-Phenylethyl isothiocyanate induces autophagy and inhibits the growth of various tumor cells. | ||
| M9631 | FITC | Fluorescent Dye |
| 5-FITC; 5-Isothiocyanato fluorescein; FITC isomer I | ||
| FITC (Fluorescein Isothiocyanate, 5-FITC) is an amine-reactive reagent for the FITC labeling of proteins, microsequencing of proteins, and peptides. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. | ||
| M9841 | 1-Naphthyl isothiocyanate | Others |
| α-Naphthyl isothiocyanate | ||
| 1-Naphthyl isothiocyanate (NITC) can be used as a source of thiourea moiety to synthesize derivatives of calixarenes to be used as anion acceptors. | ||
| M10217 | Diethyldithiocarbamate sodium | HIV Protease |
| DDC | ||
| Sodium diethyldithiocarbamate is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection. | ||
| M10267 | Sodium thiocyanate | Others |
| Sodium thiocyanate is used in the printing and dyeing and pharmaceutical industries as well as as a reagent and solvent of polyacrylonitrile, Sodium thiocyanate decreases the level of pro-inflammatory cytokine IL-6 and increases the level of anti-inflammatory cytokine IL-10. Sodium thiocyanate also significantly reduced ROS formation. | ||
| M10982 | α-Lipoic Acid | NF-κB |
| Thioctic acid | ||
| α-Lipoic Acid is an antioxidant that is an important cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum stress (ER)-mediated apoptosis of liver cancer cells. | ||
| M13761 | 5(6)-FITC | Fluorescent Dye |
| Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers | ||
| 5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of fluorescein dye that has wide-ranging applications as a label for antibodies and other probes, for use in fluorescence microscopy, flow cytometry and immunofluorescence-based assays such as Western blotting and ELISA. | ||
| M18870 | Thiocolchicine | Others |
| Thiocolchicine | ||
| M19902 | Erythromycin thiocyanate | Antibiotic |
| Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. | ||
| M19996 | Guanidine thiocyanate | Nucleic Acid Extraction and Purification |
| GTC | ||
| Guanidine thiocyanate is a catalytic solvent. Guanidine thiocyanate is useful as a protein denaturing agent and nucleic acid protectant for DNA and RNA extraction from cells. It inactivates the virus for research. | ||
| M25378 | 6-FITC | Fluorescent Dye |
| 6-Fluorescein Isothiocyanate | ||
| 6-FITC (6-Fluorescein Isothiocyanate) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. | ||
| M30406 | Balanol | PKA |
| Ophiocordin; Azepinostatin | ||
| Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC50s=4-9 nM) and ζ (IC50=150 nM). Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein (CREB) and myristoylated alanine-rich C kinase substrate (MARCKS). Balanol can be isolated from the fungus Verticillium balanoides. | ||
| M40513 | Thiocillin | Antibiotic |
| Thiocillin (high-sulfur penicillin) is a natural product antibiotic derived from a ribosome-encoded peptide. | ||
| M42364 | N-methyl-N-dithiocarboxyglucamine sodium | Metabolite/Endogenous Metabolite |
| N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. | ||
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