Sodium diethyldithiocarbamate is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Solubility||Water 100 mg/mL|
Effects of epigallocatechin gallate on diethyldithiocarbamate-induced pancreatic fibrosis in rats
Min Meng, et al. Biol Pharm Bull. 2007 Jun;30(6):1091-6. PMID: 17541159.
Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats
Yasuyuki Emori, et al. J Gastroenterol Hepatol. 2005 Jun;20(6):895-9. PMID: 15946137.
Study on free radicals and pancreatic fibrosis--pancreatic fibrosis induced by repeated injections of superoxide dismutase inhibitor
N Matsumura, et al. Pancreas. 2001 Jan;22(1):53-7. PMID: 11138971.
|Related HIV Protease Products|
Cabotegravir, also known as S/GSK1265744 or GSK744, is potent HIV integrase inhibitor.
Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM.
|Apelin-36(rat, mouse) TFA
Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist.
|HIV-1 TAT Peptide TFA
TAT TFA is a cell-penetrating peptide which derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1).
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