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Thiocolchicoside

Cat. No. M8547

All AbMole products are for research use only, cannot be used for human consumption.

Thiocolchicoside Structure

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Quality Control & Documentation
Biological Activity

Thiocolchicoside is a potent competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist with muscle relaxant, anti-inflammatory, and analgesic activity. Thiocolchicoside has also been found to suppress nuclear factor kappa B ligand (RANKL) activation of NF-KB resulting in suppression of osteoclastogenesis.

Chemical Information
Molecular Weight 563.62
Formula C27H33NO10S
CAS Number 602-41-5
Solubility (25°C) Water: 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Eleonora Nucera, et al. Immediate allergic reaction to thiocolchicoside confirmed by skin testing and basophil activation test: A case report and literature review

[2] Srgio M Martinho, et al. Visual Hallucinations After Treatment With Thiocolchicoside

[3] No authors listed. Prescrire Int. Thiocolchicoside: review of adverse effects

[4] Cumali Efe, et al. Thiocolchicoside-induced liver injury

[5] Simone Reuter, et al. Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer

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Keywords: Thiocolchicoside supplier, inhibitors, activators

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