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α-Lipoic Acid

Cat. No. M10982

All AbMole products are for research use only, cannot be used for human consumption.

α-Lipoic Acid Structure
Synonym:

Thioctic acid

Size Price Availability Quantity
500mg USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

α-Lipoic Acid is an antioxidant that is an important cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum stress (ER)-mediated apoptosis of liver cancer cells.

Chemical Information
Molecular Weight 206.33
Formula C8H14O2S2
CAS Number 1077-28-7
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bahare Salehi, et al. Biomolecules. Insights on the Use of α-Lipoic Acid for Therapeutic Purposes

[2] Wei Liu, et al. Biomed Res Int. The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases

[3] S Kucukgoncu, et al. Obes Rev. Alpha-lipoic acid (ALA) as a supplementation for weight loss: results from a meta-analysis of randomized controlled trials

[4] Nikolaos Papanas, et al. Expert Opin Pharmacother. Efficacy of α-lipoic acid in diabetic neuropathy

[5] L Packer, et al. Free Radic Biol Med. alpha-Lipoic acid as a biological antioxidant

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Keywords: α-Lipoic Acid, Thioctic acid supplier, NF-κB, inhibitors, activators

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