About 30 results found for searched term "GL3" (0.019 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40779 | Recombinant Influenza B Hemagglutinin/HA Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Recombinant Influenza B Hemagglutinin / HA Protein is a homotrimer that recognizes target cells in vertebrates and does so by binding to salivary acid-containing receptors on these cells. When it binds to the target cell, it causes the host inner membrane to fuse with the viral membrane, thereby facilitating the entry of the viral genome into the target cell. | ||
| M2346 | Filgotinib | JAK |
| GLPG0634 | ||
| Filgotinib (GLPG0634) is the first selective inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively. | ||
| M3184 | Resmetirom (MGL-3196) | Thyroid Hormone Receptor |
| VIA-3196; MGL-3196 | ||
| Resmetirom (MGL-3196, VIA-3196, resmetirom) is a potentially first-in-class, liver-targeted, orally active, selective thyroid hormone receptor (THR)-β agonist with an EC50 value of 0.21 μM. Resmetirom avoids the activation of THR-α receptors that mediate thyroid hormone activity outside of the liver, including the heart and bone. Resmetirom avoids the activation of THR-α receptors that mediate extrahepatic (including cardiac and skeletal) thyroid hormone activity and can be used in studies of non-alcoholic steatohepatitis (NASH). | ||
| M3547 | Glibenclamide | Others |
| Glyburide; RP-1127; BIIB093 | ||
| Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). | ||
| M3806 | GLYX-13 | GluR |
| Rapastinel | ||
| GLYX-13 is a selective weak partial agonist of the glycine site of the NMDA receptor. | ||
| M4648 | 12-O-Tiglylphorbol-13-isobutyrate | Others |
| The compound is extracted from Croton tiglium dried fruit. | ||
| M4668 | Astragalin | Apoptosis |
| Astragaline; 3-Glucosylkaempferol; Kaempferol 3-β-D-glucopyranoside | ||
| Astragalin (kaempferol-3-O-glucoside) is a flavonoid with anti-inflammatory activity and newly found in persimmon leaves and green tea seeds. | ||
| M4912 | GLPG0634 analogue | JAK |
| GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. | ||
| M6076 | Miquelianin | Metabolite/Endogenous Metabolite |
| Quercetin 3-O-glucuronide; Quercetin 3-glucuronide | ||
| Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid. | ||
| M6680 | DLPC | Liposome |
| 1,2-Dilauroyl-sn-glycero-3-phosphocholine | ||
| DLPC is a lRH-1 agonist; regulates bile acid metabolism. | ||
| M9097 | GLPG1837 | CFTR |
| ABBV-974; GLPG-1837 | ||
| GLPG1837 (ABBV-974) is a novel CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. | ||
| M9726 | GLX351322 | NADPH Oxidase |
| GLX351322 is an NADPH oxidase 4 inhibitor, which inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells with IC50 of 5 uM. | ||
| M9880 | 3'-MethoxyPuerarin | Others |
| Puerariaglycoside 3 | ||
| 3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity. | ||
| M9951 | DOPE | Cell Transfection |
| 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine; dioleoylphosphatidylethanolamine | ||
| DOPE (1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents. | ||
| M10119 | DOPC | Cell Transfection |
| 1,2-Dioleoyl-sn-glycero-3-phosphocholine | ||
| 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid commonly used alone or with other components in the generation of micelles, liposomes, and other types of artificial membranes. It can be used in studies related to drug delivery. | ||
| M10121 | DSPC | Cell Transfection |
| 1,2-Distearoyl-sn-glycero-3-phosphocholine | ||
| 1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system. | ||
| M10195 | MOG (35-55) (Mouse, rat) | Animal Modeling |
| Myelin Oligodendrocyte Glycoprotein (35-55) (Mouse, rat) | ||
| MOG (35-55) (Mouse, rat) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. | ||
| M10197 | (Glp1)-Apelin-13 human, bovine | Apelin Receptor |
| [Pyr1]-Apelin-13 | ||
| (Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. | ||
| M10447 | DMPC | Cell Transfection |
| 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine | ||
| 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) has the ability to enhance the constancy and in vitro antiproliferative effect of carmofur. | ||
| M11207 | GLP-1(7-37) | GLP Receptor |
| Insulinotropin (human);Peptide GLP-1 (human glucose-lowering peptide-1) | ||
| Glp-1 (7-37) is an intestinal insulin hormone that enhances glucose-induced insulin secretion. | ||
| M11319 | GLP-1(7-36), amide TFA | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | ||
| TFA is a major intestinal hormone that stimulates insulin secretion by pancreatic beta cells in response to glucose. | ||
| M11329 | AGL-2263 | Insulin Receptor |
| Agl-2263 is an inhibitor of insulin receptor and insulin-like growth factor (IGF) receptor. | ||
| M13967 | GLP-1(7-37) acetate | GLP Receptor |
| GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion. | ||
| M13968 | GLP-1(7-36), amide acetate | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate | ||
| GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. | ||
| M14232 | Rapastinel Trifluoroacetate | GluR |
| GLYX-13 Trifluoroacetate | ||
| Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. Rapastinel Trifluoroacetate has the potential for major depressive disorder treatment. | ||
| M14813 | GPRP acetate | Peptides |
| Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate | ||
| GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). | ||
| M14818 | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA | Peptides |
| MOG (35-55) (TFA) | ||
| Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (TFA) is a minor component of CNS myelin. | ||
| M14957 | 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC | Cell Transfection |
| POPC | ||
| 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers. | ||
| M17049 | Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate | Phenols |
| Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate | ||
| M17462 | 8α-Tigloyloxyhirsutinolide 13-O-acetate | Sesquiterpenoids |
| 8α-Tigloyloxyhirsutinolide 13-O-acetate | ||
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