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DMPC

Cat. No. M10447
DMPC Structure
Synonym:

1,2-Dimyristoyl-sn-glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine

Size Price Availability Quantity
100mg USD 50  USD50 In stock
250mg USD 98  USD98 In stock
500mg USD 155  USD155 In stock
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Quality Control & Documentation
Biological Activity

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) has the ability to enhance the constancy and in vitro antiproliferative effect of carmofur.

Chemical Information
Molecular Weight 677.93
Formula C36H72NO8P
CAS Number 18194-24-6
Form Solid
Solubility (25°C) Soluble in chloroform
Storage -20°C, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ilona Domracheva, et al. Toxicol Rep. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) increases Carmofur stability and in vitro antiproliferative effect

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Keywords: DMPC, 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine supplier, Cell Transfection, inhibitors, activators


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