Free shipping on all orders over $ 500

GLP-1(7-37) acetate

Cat. No. M13967
GLP-1(7-37) acetate Structure
Size Price Availability Quantity
1mg USD 128  USD128 In stock
5mg USD 250  USD250 In stock
10mg USD 375  USD375 In stock
25mg USD 720  USD720 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.

Chemical Information
Molecular Weight 3415.72
CAS Number 1450806-98-0
Solubility (25°C) Water 50 mg/mL (ultrasonic and adjust pH to 1 with HCl)
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] H Qi, et al. Stability and stabilization of insulinotropin in a dextran formulation

[2] M Lu, et al. The role of the free cytosolic calcium level in beta-cell signal transduction by gastric inhibitory polypeptide and glucagon-like peptide I(7-37)

Related GLP Receptor Products
GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat)

GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) is a biotinylated GLP-1 fragment, corresponding to the 7-36 sequence of GLP-1.

(Asp28)-Exenatide

(Asp28)-Exenatide is a degradation product of exenatide.

GLP-1 (1-36) amide (human, rat)

GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide.

Albiglutide fragment

Albiglutide fragment (GLP-1 (7-36) analog) is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist).

Pegloxenatide

Pegloxenatide is a glucagon-like peptide-1 receptor (GLP-1 RA) agonist.

  Catalog
Abmole Inhibitor Catalog




Keywords: GLP-1(7-37) acetate supplier, GLP Receptor, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.