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GLP-1(7-37) acetate

Cat. No. M13967
GLP-1(7-37) acetate Structure
Size Price Availability Quantity
1mg USD 128  USD128 In stock
5mg USD 250  USD250 In stock
10mg USD 375  USD375 In stock
25mg USD 720  USD720 In stock
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Quality Control & Documentation
Biological Activity

GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.

Chemical Information
Molecular Weight 3415.72
CAS Number 1450806-98-0
Solubility (25°C) Water 50 mg/mL (ultrasonic and adjust pH to 1 with HCl)
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] H Qi, et al. Stability and stabilization of insulinotropin in a dextran formulation

[2] M Lu, et al. The role of the free cytosolic calcium level in beta-cell signal transduction by gastric inhibitory polypeptide and glucagon-like peptide I(7-37)

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Keywords: GLP-1(7-37) acetate supplier, Glucagon Receptor, inhibitors, activators

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