Glp-1 (7-37) is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
|Solubility (25°C)||Water ≥ 20 mg/mL|
|Storage||-20°C,protect from light, dry, sealed|
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
 Torsten P Vahl, et al. J Clin Endocrinol Metab. Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans
|Related GLP Receptor Products|
|GLP-1 receptor agonist 12
GLP-1 receptor agonist 12 is an agonist of GLP Receptor.
|GLP-1 receptor agonist 11
GLP-1 receptor agonist 11 is an agonist of GLP Receptor.
|GLP-1 receptor agonist 10
GLP-1 receptor agonist 10 is an agonist of GLP Receptor.
|GLP-1 receptor agonist 13
GLP-1 receptor agonist 13 is a glucagon GLP-1 receptor agonist with EC50 of 76 nM.
LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein–protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.