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GLX351322 is an NADPH oxidase 4 inhibitor, which inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells with IC50 of 5 uM. GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice.
| Molecular Weight | 431.51 |
| Formula | C21H25N3O5S |
| CAS Number | 835598-94-2 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 15 mg/mL |
| Storage | -20°C, dry, sealed |
| Related NADPH Oxidase Products |
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| Fluoflavine
Fluoflavine is a selective NOX1 inhibitor with an IC50 value of 90 nM.Fluoflavine is >100 times more selective for NOX1 than NOX2, NOX3, NOX4, and has an IC50 >10 μM for all of them.Fluoflavine was shown to be a selective inhibitor of NOX1 with an IC50 of 360 nM in HEK293 cells. |
| NoxA1ds
NoxA1ds is a highly efficacious and selective Nox1 (NADPH oxidase isoform 1) inhibitor. |
| GLX481369
GLX481369 is a redox active substance. |
| Noxa B BH3
Noxa B BH3 is a biological active peptide. |
| Noxa A BH3
Noxa A BH3 is a biological active peptide. |
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