About 30 results found for searched term "EI1" (0.018 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4262 | Tubeimoside-I | Apoptosis |
| Tubeimoside-1; Lobatoside-H | ||
| Tubeimoside I, an extract of Fritillaria fritillaria, has been proved to be an effective antitumor agent for various human cancers. | ||
| M4271 | Delavinone | Others |
| Sinpeimine; CAS# 103530-47-8 | ||
| Delavinone | ||
| M7400 | Teijin compound 1 | Others |
| Teijin compound 1 is a potent CCR2b antagonist. | ||
| M45313 | Casein kinase 1δ-IN-5 | Casein Kinase |
| Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM, which has neuroprotective and anti-inflammatory properties in vitro. It has neuroprotective and anti-inflammatory properties in vitro. It can be used in studies related to neurodegenerative diseases. | ||
| M9004 | WDR5-0103 | Histone Methyltransferase |
| WD-Repeat Protein 5-0103 | ||
| WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 µM). | ||
| M9537 | Protein kinase inhibitors 1 | DYRK |
| Protein kinase inhibitors I | ||
| Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | ||
| M9605 | Molnupiravir (EIDD-2801) | Anti-infection |
| MK-4482; pro-EIDD-1931; CAS#2492423-29-5 | ||
| Molnupiravir (EIDD-2801) is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. | ||
| M9736 | VHL Ligand 1 hydrochloride | Ligand for E3 Ligase |
| Protein degrader 1; VH032-NH2 hydrochloride; (S,R,S)-AHPC hydrochloride | ||
| VHL Ligand 1 hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. | ||
| M21525 | Recombinant Mouse S100A11 (E.coli , N-6His) | Cytokines and Growth Factors |
| Protein S100-A11; Calgizzarin; Endothelial monocyte-activating polypeptide | ||
| The recombinant mouse protein S100-A11 was produced by the Escoli expression system, and the target gene Met1-Ile98 was expressed with 6His marker at the n terminal. Protein number: P50543. | ||
| M10194 | Amyloid β Protein 1-40 (TFA) | Amyloid |
| β-Amyloid (1-40) ; Beta-amyloid (1-40) | ||
| β-Amyloid (1-40) TFA is a major protein fragment found in brain plaques of Alzheimer's disease. | ||
| M11232 | Recombinant Mouse Beta-NGF Protein (110AA, E. coli) | Cytokines and Growth Factors |
| β-NGF; NGFB | ||
| Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. | ||
| M11242 | EI1 | Histone Methyltransferase |
| KB-145943 | ||
| EI1 (KB-145943) is a novel and effective EZH2 inhibitor, capable of acting on EZH2 (WT) and EZH2 (Y641F) with IC50 values of 15 nM and 13 nM, respectively. | ||
| M11259 | Cefminox sodium | Antibiotic |
| Meicelin, MT-141 | ||
| Cefminox Sodium (MT-141) is a semi-synthetic cephalomycin with a broad spectrum of antibacterial activities. Cefminox sodium (MT-141) is a dual agonist of prostacyclin receptor and PPARγ, which can up-regulate cAMP production and PTEN expression, and inhibit Akt/mTOR signaling pathway. Cefminox sodium (MT-141) can inhibit pulmonary hypertension. | ||
| M11489 | Recombinant Human MCP-1/CCL2 (E. coli) | Cytokines and Growth Factors |
| MCAF; JE; Monocyte Chemotactic Protein-1; CCL2; MCP1 | ||
| The EC50 value of human MCP-1/CCL2 on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR2 cells (human Gα15 and human CCR2 stably expressed in CHO-K1 cells) is less than 1.0 μg/ml. Accession # : P13500. | ||
| M11533 | Recombinant Human DKK-1 (HEK293, N-8His) | Cytokines and Growth Factors |
| Dickkopf-related protein 1;Dickkopf-1;Dkk-1 | ||
| Dickkopf-related protein 1(DKK-1) secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. | ||
| M13445 | Peripheral Myelin P0 Protein (180-199), mouse | Peptides |
| Peripheral Myelin P0 Protein (180-199), mouse is a neurogenic peptide purified from Peripheral Myelin of mice. Sequence：Ser-Ser-Lys-Arg-Gly-Arg-Gln-Thr-Pro-Val-Leu-Tyr-Ala-Met-Leu-Asp-His-Ser-Arg-Ser | ||
| M15023 | Recombinant Human MCP-2/CCL8 (E. coli) | Cytokines and Growth Factors |
| Monocyte Chemoattractant Protein-2; HC14; SCYA8 | ||
| McP-2, a member of the chemokine family, is a group of 70-80 residues with significant sequence similarity. Protein structure: McP-2 (GLN24-PRO99), Accession # P80075. | ||
| M15025 | Recombinant Mouse MIP-1α/CCL3 (HEK 293) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| MIP-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA24-ALA92), Accession # : Q5QNW0. | ||
| M13660 | eIF4A3-IN-1 | Others |
| eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. | ||
| M15024 | Recombinant Human MIP-1α/CCL3 (CHO) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| Mip-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA27-ALA92), Accession # : P10147. | ||
| M15054 | Recombinant Mouse DCIP-1/CXCL3 (CHO) | Cytokines and Growth Factors |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1 | ||
| Chemokine (C-X-C Motif) ligand 3 (CXCL3) is a small cytokine in the CXC chemokine family, also known as DCIP-1(Dendritic cell inflammatory protein-1) or MIP-2B. Protein structure: CXCL3 (ALA28-SER100), Accession # : Q6W5C0. | ||
| M13928 | CCR2 antagonist 4 | CCR |
| Teijin compound 1 | ||
| CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. | ||
| M15026 | Recombinant Human MIP-1β /CCL4 (E. coli) | Cytokines and Growth Factors |
| MIP-1 beta; Macrophage Inflammatory Protein-1β; CCL-4; ACT-2 | ||
| Macrophage inflammatory protein 1β (MIP-1β), also known as Chemokine (C-motif) ligand 4 (CCL4), is a small cytokine in the CC Chemokine family. It is a chemical attractant for natural killer cells, monocytes and a variety of other immune cells. Protein structure: MIP-1β (ALA24-ASN92), Accession # P13236-1. | ||
| M15055 | Recombinant Mouse CXCL3 (E. coli, His Tag) | Cytokines and Growth Factors |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1; DCIP-1 | ||
| Dendritic cell inflammatory protein-1 (DCIP-1)/CXCL3 is also known as MIP2β(macrophage inflammatory protein 2 beta) or DCIP1(Dendritic cell inflammatory protein 1) in mice and CINC2(cytodynamics-induced neutrophil attractant 2) in rats, In humans it is known as GRO gamma (Growth regulated oncogene gamma). | ||
| M15053 | Recombinant Mouse CCL2/MCP-1 (E.coli) | Cytokines and Growth Factors |
| C-C motif chemokine 2; Monocyte chemoattractant protein 1 | ||
| Recombinant mouse C-C Motif Chemokine 2, produced by escherichia coli expression system, expressed the target gene encoding GLN24-ARG96. Accession # : P10148. | ||
| M14511 | LEI-401 | Phospholipase |
| LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. | ||
| M14561 | Recombinant Human MIP-5/CCL15 Protein (E. coli, aa 22-113, C-His) | Cytokines and Growth Factors |
| SCYA15; HCC-2; NCC-3 | ||
| Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. | ||
| M15012 | Recombinant Human TIMP-2 (HEK293,C-6His) | Cytokines and Growth Factors |
| Metalloproteinase Inhibitor 2; CSC-21K | ||
| TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities. | ||
| M14890 | Protein kinase inhibitors 1 hydrochloride | Others |
| Protein kinase inhibitors 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2. | ||
| M15067 | Recombinant Human FGF-4 (153AA, E.coli) | Cytokines and Growth Factors |
| Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1 | ||
| Recombinant human fibroblast growth factor 4 is produced by the escherichia coli expression system and expresses the target gene encoding SER54-LEU206. Accession # : P08620. | ||
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