About 30 results found for searched term "EI1" (0.033 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4262 | Tubeimoside-I | Apoptosis |
| Tubeimoside-1; Lobatoside-H | ||
| Tubeimoside I, an extract of Fritillaria fritillaria, has been proved to be an effective antitumor agent for various human cancers. | ||
| M4271 | Delavinone | Others |
| Sinpeimine; CAS# 103530-47-8 | ||
| Delavinone | ||
| M7400 | Teijin compound 1 | Others |
| Teijin compound 1 is a potent CCR2b antagonist. | ||
| M45313 | Casein kinase 1δ-IN-5 | Casein Kinase |
| Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM, which has neuroprotective and anti-inflammatory properties in vitro. It has neuroprotective and anti-inflammatory properties in vitro. It can be used in studies related to neurodegenerative diseases. | ||
| M9004 | WDR5-0103 | Histone Methyltransferase |
| WD-Repeat Protein 5-0103 | ||
| WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 µM). | ||
| M9537 | Protein kinase inhibitors 1 | DYRK |
| Protein kinase inhibitors I | ||
| Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | ||
| M9605 | Molnupiravir (EIDD-2801) | Anti-infection |
| MK-4482; pro-EIDD-1931; CAS#2492423-29-5 | ||
| Molnupiravir (EIDD-2801) is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. | ||
| M9736 | VHL Ligand 1 hydrochloride | Ligand for E3 Ligase |
| Protein degrader 1; VH032-NH2 hydrochloride; (S,R,S)-AHPC hydrochloride | ||
| VHL Ligand 1 hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. | ||
| M21525 | Recombinant Mouse S100A11 (E.coli , N-6His) | Cytokines and Growth Factors |
| Protein S100-A11; Calgizzarin; Endothelial monocyte-activating polypeptide | ||
| The recombinant mouse protein S100-A11 was produced by the Escoli expression system, and the target gene Met1-Ile98 was expressed with 6His marker at the n terminal. Protein number: P50543. | ||
| M10194 | Amyloid β Protein 1-40 (TFA) | Amyloid |
| β-Amyloid (1-40) ; Beta-amyloid (1-40) | ||
| β-Amyloid (1-40) TFA is a major protein fragment found in brain plaques of Alzheimer's disease. | ||
| M66312 | CAVIN1 Human Pre-designed siRNA Set | siRNA |
| caveolae associated protein 1 | ||
| Human CAVIN1 Pre-designed siRNA Set contains three designed siRNAs for CAVIN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 284119 | ||
| M11232 | Recombinant Mouse Beta-NGF Protein (110AA, E. coli) | Cytokines and Growth Factors |
| β-NGF; NGFB | ||
| Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. | ||
| M11242 | EI1 | Histone Methyltransferase |
| KB-145943 | ||
| EI1 (KB-145943) is a novel and effective EZH2 inhibitor, capable of acting on EZH2 (WT) and EZH2 (Y641F) with IC50 values of 15 nM and 13 nM, respectively. | ||
| M11259 | Cefminox sodium | Antibiotic |
| Meicelin, MT-141 | ||
| Cefminox Sodium (MT-141) is a semi-synthetic cephalomycin with a broad spectrum of antibacterial activities. Cefminox sodium (MT-141) is a dual agonist of prostacyclin receptor and PPARγ, which can up-regulate cAMP production and PTEN expression, and inhibit Akt/mTOR signaling pathway. Cefminox sodium (MT-141) can inhibit pulmonary hypertension. | ||
| M11489 | Recombinant Human MCP-1/CCL2 (E. coli) | Cytokines and Growth Factors |
| MCAF; JE; Monocyte Chemotactic Protein-1; CCL2; MCP1 | ||
| The EC50 value of human MCP-1/CCL2 on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR2 cells (human Gα15 and human CCR2 stably expressed in CHO-K1 cells) is less than 1.0 μg/ml. Accession # : P13500. | ||
| M11533 | Recombinant Human DKK-1 (HEK293, N-8His) | Cytokines and Growth Factors |
| Dickkopf-related protein 1;Dickkopf-1;Dkk-1 | ||
| Dickkopf-related protein 1(DKK-1) secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. | ||
| M13445 | Peripheral Myelin P0 Protein (180-199), mouse | Peptides |
| Peripheral Myelin P0 Protein (180-199), mouse is a neurogenic peptide purified from Peripheral Myelin of mice. Sequence：Ser-Ser-Lys-Arg-Gly-Arg-Gln-Thr-Pro-Val-Leu-Tyr-Ala-Met-Leu-Asp-His-Ser-Arg-Ser | ||
| M15023 | Recombinant Human MCP-2/CCL8 (E. coli) | Cytokines and Growth Factors |
| Monocyte Chemoattractant Protein-2; HC14; SCYA8 | ||
| McP-2, a member of the chemokine family, is a group of 70-80 residues with significant sequence similarity. Protein structure: McP-2 (GLN24-PRO99), Accession # P80075. | ||
| M15025 | Recombinant Mouse MIP-1α/CCL3 (HEK 293) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| MIP-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA24-ALA92), Accession # : Q5QNW0. | ||
| M13660 | eIF4A3-IN-1 | Others |
| eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. | ||
| M15024 | Recombinant Human MIP-1α/CCL3 (E. coli) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| Mip-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1α belongs to the CCL chemokine family and has 68% homology with MIP-1β. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. | ||
| M15054 | Recombinant Mouse DCIP-1/CXCL3 (CHO) | Cytokines and Growth Factors |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1 | ||
| Chemokine (C-X-C Motif) ligand 3 (CXCL3) is a small cytokine in the CXC chemokine family, also known as DCIP-1(Dendritic cell inflammatory protein-1) or MIP-2B. Protein structure: CXCL3 (ALA28-SER100), Accession # : Q6W5C0. | ||
| M13928 | CCR2 antagonist 4 | CCR |
| Teijin compound 1 | ||
| CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. | ||
| M15026 | Recombinant Human MIP-1β /CCL4 (E. coli) | Cytokines and Growth Factors |
| MIP-1 beta; Macrophage Inflammatory Protein-1β; CCL-4; ACT-2 | ||
| Macrophage inflammatory protein 1β (MIP-1β), also known as Chemokine (C-motif) ligand 4 (CCL4), is a small cytokine in the CC Chemokine family. It is a chemical attractant for natural killer cells, monocytes and a variety of other immune cells. Protein structure: MIP-1β (ALA24-ASN92), Accession # P13236-1. | ||
| M15055 | Recombinant Mouse CXCL3 (E. coli, His Tag) | Cytokines and Growth Factors |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1; DCIP-1 | ||
| Dendritic cell inflammatory protein-1 (DCIP-1)/CXCL3 is also known as MIP2β(macrophage inflammatory protein 2 beta) or DCIP1(Dendritic cell inflammatory protein 1) in mice and CINC2(cytodynamics-induced neutrophil attractant 2) in rats, In humans it is known as GRO gamma (Growth regulated oncogene gamma). | ||
| M15053 | Recombinant Mouse CCL2/MCP-1 (E.coli) | Cytokines and Growth Factors |
| C-C motif chemokine 2; Monocyte chemoattractant protein 1 | ||
| Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. CCL2 is implicated in the pathogeneses of several types of disease characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis. | ||
| M14511 | LEI-401 | Phospholipase |
| LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. | ||
| M14561 | Recombinant Human MIP-5/CCL15 Protein (E. coli, aa 22-113, C-His) | Cytokines and Growth Factors |
| SCYA15; HCC-2; NCC-3 | ||
| Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. | ||
| M15012 | Recombinant Human TIMP-2 (HEK293,C-6His) | Cytokines and Growth Factors |
| Metalloproteinase Inhibitor 2; CSC-21K | ||
| TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities. | ||
| M14890 | Protein kinase inhibitors 1 hydrochloride | Others |
| Protein kinase inhibitors 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2. | ||
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