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Teijin compound 1

Cat. No. M7400

All AbMole products are for research use only, cannot be used for human consumption.

Teijin compound 1 Structure

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Quality Control & Documentation
Biological Activity

Teijin compound 1 is a potent chemokine CCR2b receptor antagonist (IC50 = 180 nM). Potently inhibits cell chemotaxis induced by MCP-1 (EC50 = 24 nM).

Chemical Information
Molecular Weight 476.32
Formula C21H21ClF3N3O2.HCl
CAS Number 1313730-14-1
Solubility (25°C) Water 4.76 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] McGuire, et al. J Biol Chem. Platelet-derived growth factor receptor tyrosine kinase phosphorylation requires protein geranylgeranylation but not farnesylation.

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Keywords: Teijin compound 1 supplier, inhibitors, activators

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