| Cat.No. | Name | Information |
|---|---|---|
| M3386 | Amiloride hydrochloride | Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. |
| M3366 | Amiloride hydrochloride dihydrate | Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. |
| M2487 | Camostat Mesilate | Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase. |
| M2380 | Ambroxol hydrochloride | AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. |
| M2264 | Oxcarbazepine | Oxcarbazepine is an anticonvulsant and mood-stabilizing compound. |
| M2210 | A-803467 | A-803467 is a potent and selective Nav1.8 sodium channel blocker that potently blocks tetrodotoxin-resistant currents (IC50 = 140 nM). |
| M1968 | Riluzole | Rilutek is a sodium channel protein inhibitor and a new mental compound, which has anticonvulsant, hypnotic, antianxiety, antiischemia and anesthesia properties. Riluzole belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM. |
| M1427 | Lacosamide | Lacosamide is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. |
| M54821 | ASN008 | ASN008 is a permanently positively charged sodium channel blocker. |
| M53703 | Psalmotoxin 1 | Psalmotoxin 1 (PcTx1) is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). |
| M52723 | Jingzhaotoxin-III | Jingzhaotoxin-III is a potent and selective blocker of Nav1.5 channels, with an IC50 of 348 nM, and shows no effect on other sodium channel isoforms. |
| M52722 | Huwentoxin-IV | Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively. |
| M52721 | Phrixotoxin 3 | Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC50s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. |
| M52720 | APETx2 | APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC50 of 63 nM. |
| M52719 | β-Pompilidotoxin | β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells. |
| M52718 | µ-Conotoxin-CnIIIC | μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. |
| M52717 | µ-Conotoxin KIIIA | μ-Conotoxin KIIIA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. |
| M52716 | µ-Conotoxin SIIIA | μ-Conotoxin SIIIA is a tetrodotoxin (TTX)-resistant sodium channel blocker. |
| M52715 | ω-Conotoxin CVIB | ω-Conotoxin CVIB is a non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) antagonist. |
| M52714 | μ-Conotoxin PIIIA | μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. |
| M52713 | µ-Conotoxin GIIIB | μ-Conotoxin GIIIB is a 22-residue polypeptide that can be isolated from the venom of piscivorous cone snail Conus geographus. |
| M52712 | µ-Conotoxin BuIIIC | μ-Conotoxin BuIIIC (Mu-Conotoxin BuIIIC) is a potent Nav1.4 inhibitor. |
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