| Cat.No. | Name | Information |
|---|---|---|
| M3386 | Amiloride hydrochloride | Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. |
| M3366 | Amiloride hydrochloride dihydrate | Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. |
| M52711 | µ-Conotoxin BuIIIB | μ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB) is a mammalian neuronal voltage-gated sodium channel (VGSC) blocker. |
| M52710 | μ-Conotoxin Sx IIIA | μ-Conotoxin Sx IIIA is a biological active peptide. |
| M52709 | Hainantoxin-III | Jingzhaotoxin-V is a peptide that inhibits potassium currents in Xenopus laevis oocytes with an IC50 value of 604.2 nM. |
| M52708 | Hainantoxin-IV | Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. |
| M52707 | Ceratotoxin-2 | Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively. |
| M52706 | Mambalgin 1 | Mambalgin-1 is a toxin isolated from black mamba venom. |
| M52705 | GpTx-1 | GpTx-1 is a potent and selective NaV1.7 antagonist with an IC50 of 10 nM. |
| M50232 | LTGO-33 | LTGO-33 is a potent, selective NaV1.8 inhibitor for pain-related studies. |
| M49943 | PF-06305591 dihydrate | PF-06305591 dihydrate is a potent, highly selective blocker of the voltage-gated sodium channel NaV1.8 with an IC50 value of 15 nM for pain-related studies. |
| M49942 | PF-06305591 | PF-06305591 is a potent and highly selective blocker of the voltage-gated sodium channel NaV1.8 with an IC50 value of 15 nM for pain-related studies. |
| M49941 | VX-128 | VX-128 is a Nav1.8 blocker that can be used in studies related to acute pain. |
| M49823 | PRAX-628 | PRAX-628 is a potential best-in-class, selective small molecule inhibitor of sodium channels that targets sodium channels in the brain in a hyperexcitable state. It can be used in studies related to focal epilepsy. |
| M49486 | BI 1265162 | BI 1265162 is a selective epithelial sodium channel (ENaC) inhibitor for studies related to cystic fibrosis (CF). |
| M49403 | Relutrigine | Relutrigine is an orally active, persistent sodium channel inhibitor that potently and preferentially inhibits persistent INa induced by ATX-II (Nav 1.5 activator) or the SCN8A mutation N1768D with IC50 values of 141 nM and 75 nM, respectively. |
| M49397 | ATX-II TFA | ATX-II TFA, a specific Na+ channel modulator toxin derived from sea anemone (Anemonia sulcata) venom, causes sensitization of cell cultures to Na+Halothane , Caffeine, and Ryanodine. In addition, ATX-II induces pulmonary venous arrhythmias and atrial fibrillation. |
| M42258 | Aah II | Aah II is a sodium channel modulator. |
| M42257 | Ancistrotecine B | Ancistrotecine B is a Nav1.7 channel inhibitor (IC50: 0.73 μM). |
| M42256 | Hm1a | Hm1a is a disulfide-rich spider-venom peptide, and a NaV1.1 activator. |
| M42255 | Aneratrigine | Aneratrigine is a sodium channel protein type 9 subunit alpha blocker. |
| M42254 | Dc1a | Dc1a potently promotes opening of the German cockroach Nav channel (BgNav1). |
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