| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M21294 | OI338 | OI338 is an oral, long-acting insulin analogue. |
| M21279 | MK-5204 | MK-5204 is a broad spectrum Candida antifungal agent derived from the natural product, enfumafungin. |
| M21269 | EC2629 | EC2629 is a folate receptor (FR)-targeting small molecule drug conjugate with a folate receptor-targeting molecule, a pyrrole-ring benzodiazepine (PBD) DNA cross-linked warhead and a linker. |
| M21268 | ETX0282 | ETX0282 is an oral prodrug of a class A, C and D serine beta-lactamase inhibitor in clinical development in combination with the beta-lactam drug cefpodoxime proxetil. |
| M21266 | MGS0274 | MGS0274 is a lipid-soluble precursor drug for the mGlu2 and mGlu3 receptor agonist MGS0008, which improves oral bioavailability. mGS0274 has potential for use in the study of schizophrenia. |
| M21263 | X-165 | X-165 is a clinical candidate compound for the study of autologous cell inhibitors in idiopathic pulmonary fibrosis, which was discovered through a 3-cycle DEL screen of 225M compounds obtained from amide coupling. |
| M21261 | Xeruborbactam | Xeruborbactam (QPX7728) is a potent, ultra-broad-spectrum inhibitor of boronic acid beta-lactamase. xeruborbactam inhibits serine and metallo-beta-lactamases in the nanomolar range. |
| M21258 | S6821 | S6821 is one of the two potent and selective TAS2R8 GPCR antagonists disclosed. |
| M21257 | MK-6884 | MK-6884 is an M4 muscarinic receptor orthomodulator (PAM) with a Ki value of 0.19 nM. MK-6884 is used in the study of neurodegenerative diseases. MK-6884 can be used as a positron emission computed tomography imaging agent with 11C radiolabeling. |
| M21256 | CD73-IN-2 | CD73-IN-2 is a potent CD73 inhibitor with an IC50 of 0.09 nM. |
| M21229 | BMS-986260 | BMS-986260 is a potent, selective, orally available TGFβR1 inhibitor with an IC50 of 1.6 nM. |
| M21219 | Maralixibat chloride | Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. (IBAT) is used in the study of rare cholestatic liver diseases, including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. |
| M21217 | (-)-JNJ-A07 | (-)-JNJ-A07 is a potent and selective inhibitor of dengue virus (DENV) with an EC50 of 31 nM. |
| M21216 | (+)-JNJ-A07 | (+)-JNJ-A07 is a potent pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against 21 clinical isolates. (+)-JNJ-A07 has a good pharmacokinetic profile and showed significant efficacy against dengue virus infection in a mouse infection model. |
| M21199 | Intralipid | Intralipid is an emulsion containing soybean oil, glycerol, and soy phosphatides. Intralipid is a safe fat emulsion that can be used as a nutritional supplement. Intralipid effectively inhibits the opening of the mitochondrial permeability transition pore. |
| M21196 | FRM-024 | FRM-024 is a potent CNS-permeable gamma-secretase modulator and a candidate for familial Alzheimer's disease. |
| M21195 | JNJ-67569762 | JNJ-67569762 is a selective BACE1 inhibitor targeting S3 (IC50 = 2.7 nM). It is a preclinical candidate compound for the study of Alzheimer's disease. |
| M21190 | ETX0462 | ETX0462 is a Gram-negative chemotypic antibiotic.ETX0462 has potent in vitro and in vivo activity against Pseudomonas aeruginosa and all other Gram-negative ESKAPE pathogens, Stenotrophomonas maltophilia, and biothreat pathogens. |
| M21179 | TAK-071 | TAK-071 is a novel, potent and selective modulator of muscarinic acetylcholine receptor 1 (M1R) orthostructure. TAK-071 activates M1R with an EC50 of 520 nM. |
| M21174 | Ledaborbactam etzadroxil | Serine_lactamase inhibitor VNRX-7145 is an oral biologic formulation of the boronic acid-containing inhibitor VNRX-5236, currently in Phase I. |
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