Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
M8074 | PF-06454589 | PF-06454589 is a potent and selective LRRK2 inhibitor. |
M8073 | PF-04979064 | PF-04979064 is an orally available, potent and selective PI3K/mTOR dual kinase inhibitor that potently inhibits tumor growth in mouse xenografts. |
M8072 | PF-06672131 | PF-06672131 is a selective EGFR kinase inhibitor thought to covalently react with active-site cysteine residues in the ATP binding pocket. |
M8071 | PF-6422899 | PF-6422899 is an alkynylated derivative of PF-6274484; irreversible inhibitor of EGFR kinase activity. |
M8070 | CP-863187 | CP-863187 is a potent p38α (p38α) inhibitor (IC50 = 5. |
M8068 | CP 524515 | CP-524515 is a potent inhbitor of cholesteryl ester transfer protein (CETP) that leads to elevated high-density lipoprotein cholesterol levels. |
M8067 | CP 532623 | CP-532623 is a potent inhbitor of cholesteryl ester transfer protein (CETP) that leads to elevated high-density lipoprotein cholesterol levels. |
M8066 | PF-06297470 | PF-06297470 is a potent negative allosteric modulator of the Metabotropic Glutamate Receptor 5 (mGluR5). |
M8065 | PF-5081090 | PF-5081090 is a potent inhibitor of LpxC, a metalloenzyme required for the synthesis of lipid A, an essential component of the outer membrane of Gram-negative bacteria. |
M8064 | OSU6162 hydrochloride | OSU6162 (PNU-96391) is a dopamine stabilizer, a drug that can stimulate or inhibit dopaminergic signaling depending on the dopaminergic tone. |
M8063 | Gisadenafil besylate salt | Gisadenafil (UK 369003) is a PDE5 inhibitor. |
M8061 | SU5614 | SU5614 is a FMS-like tyrosine kinase 3 (FLT3) inhibitor; selective inhibitor of VEGF and PDGF receptor tyrosine kinases. |
M8060 | CP-868388 | CP-868388 is a potent PPARα agonist with a Ki of 10. |
M8059 | PD-180970 | PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase. |
M8058 | PD-156707 | PD-156707 is a selective endothelin receptor (ETA) antagonist. |
M8057 | EBPC | EBPC is an aldose reductase inhibitor; anti-cancer. |
M8056 | CP-471474 | CP-471474 is a broad spectrum inhibitor of matrix metalloproteinases. |
M8055 | PHA-543613 | PHA-543613 is a potent selective α7 nAChR agonist. |
M8054 | SC-51322 | SC-51322 is a selective EP1 prostanoid receptor antagonist. |
M8053 | PF-998425 | PF-998425 is a novel, nonsteroidal androgen receptor antagonist. |
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