| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
| M7955 | Nucleozin | Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. |
| M7954 | NP603 | NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. |
| M7953 | NKY80 | NKY80 is a selective adenylyl cyclase-V inhibitor with greater than 200-fold selectivity for type V over the type II isoform. |
| M7951 | Naltrindole isothiocyanate hydrochloride | Naltrindole isothiocyanate hydrochloride is a selective irreversible δ2 opioid receptor antagonist. |
| M7948 | NO-711 hydrochloride | NO-711 is a potent and selective GABA uptake inhibitor that crosses the blood-brain barrier. |
| M7947 | NSCI | NSCI is a nonpeptide caspase 3 selective inhibitor. |
| M7946 | Naloxone methiodide | Quaternary salt of naloxone that, like the parent compound, is a nonselective antagonist at opioid receptors. |
| M7944 | NSC43067 | NSC43067 is a Cyclin-dependent kinase (Cdk) inhibitor which binds to a novel conserved site on Cdk, presumably the p27 binding pocket. |
| M7943 | NAEPA | Selective lysophosphatidic acid-1 (LPA1) receptor agonist; LPA mimetic. |
| M7941 | H-8 dihydrochloride | cAMP and cGMP-dependent protein kinase inhibitor. |
| M7937 | MADAM dihydrochloride | High affinity ligand for the serotonin transporter SERT. |
| M7935 | ML 10302 | Potent, selective 5-HT4 serotonin receptor agonist. |
| M7933 | (+)-Muscarine chloride | Prototype muscarinic acetylcholine receptor agonist; active enantiomer. |
| M7932 | MRS 2395 | Antagonist for P2Y12 purinoceptor; inhibits ADP-induced aggregation in rat platelets and antagonizes ADP-induced inhibition of cAMP in rat and human platelets in the presence of PGE1 without affecting P2Y1 receptor-induced PLC activity in transfected astrocytoma cells. |
| M7931 | MBX-102 acid | MBX-102 is a selective PPAR modulator (SPPARM) and has been shown to inhibit phosphorylation of PPARγ. |
| M7930 | Metrazoline | Potent and selective imidazoline binding site ligand. |
| M7928 | E-4031 | E-4031 selectively blocks hERG K+ channels. |
| M7924 | Metergoline | Antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors; analgesic; antipyretic. |
| M7923 | Myoseverin B | Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. |
| M7922 | MJ33 lithium salt | Novel, active site directed, specific, competitive and reversible inhibitor of phospholipase A2 (PLA2). |
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