Catalog

NLR NOD-like Receptor

Inhibitors

Cat.No.	Name	Information
M10136	GSK717	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor.
M9516	INF39	INF39 is a nontoxic, irreversible NLRP3 inhibitor able to decrease interleukin-1β release from macrophages.
M9263	CY-09	CY-09 is a selective and direct NLRP3 inhibitor.
M8083	CP-456773 sodium salt	CP-456773 sodium salt (MCC950) was found to act as a cytokine release inhibitory drug and inhibitor of the NLRP3 inflammasome.
M7547	NOD-IN-1	NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
M6164	MCC950	MCC950 is a potent, selective NLRP3 inhibitor with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively.
M5301	Cardamonin	Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM, Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.