| Cat.No. | Name | Information |
|---|---|---|
| M5301 | (E)-Cardamonin | (E)-Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM, Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. |
| M54567 | VENT-01 | VENT-01 is an NLRP3 inhibitor for studies related to non-alcoholic steatohepatitis (NASH) and chronic kidney disease. |
| M54538 | NT-0249 | NT-0249 is an NLRP3 inhibitor that can be used in studies related to inflammation. |
| M45277 | VTX-2735 | VTX-2735 is an NLRP3 inhibitor that can be used in studies related to inflammatory diseases. |
| M45276 | Somalix | Somalix is an orally active, peripherally restricted NLRP3 inhibitor for studies related to arthritis and inflammatory diseases. |
| M45275 | IFM-2427 | IFM-2427 is an NLRP3 inhibitor that can be used in studies related to non-alcoholic steatohepatitis (NASH) and gout. |
| M42028 | iE-DAP | iE-DAP is a biological active peptide. |
| M42027 | NLRP3-IN-9 | NLRP3-IN-9 is a potent NLRP3 inhibitor. |
| M42026 | JT002 | JT002 is an orally active inhibitor of the NLRP3 inflammasome. |
| M42025 | NLRP3-IN-18 | NLRP3-IN-18 is a potent NLRP3 inhibitor with an IC50 value of ≤1.0 µM. |
| M42024 | TriDAP | TriDAP (L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a biological active peptide. |
| M42023 | NLRP3-IN-19 sodium | NLRP3-IN-19 (JT001) is a potent, specific and orally active inhibitor of NLRP3. |
| M42022 | NLRP3-IN-19 | NLRP3-IN-19 (JT001) is a potent, specific and orally active inhibitor of NLRP3. |
| M42021 | INF200 | INF200 is a sulfonylurea-based inhibitor of NLRP3 and NLRP3-mediated pyroptosis. |
| M42020 | Selnoflast calcium | Selnoflast calcium is a NLRP3 inhibitor (extracted from patent WO2019008025). |
| M42019 | Usnoflast | Usnoflast is a NLRP3 modulator, as well as a non-steroidal anti-inflammatory agent (NSAD). |
| M42018 | Selnoflast potassium | Selnoflast (potassium) is a NLRP3 inhibitor (extracted from patent WO2019008025). |
| M42017 | M-TriDAP | M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a biological active peptide. |
| M42016 | NLRP3-IN-17 | NLRP3-IN-17 is a potent, selective and orally active NLRP3 inflammasome inhibitor with an IC50 value of 7 nM. |
| M30978 | Fc 11a-2 | Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium (DSS)-induced murine experimental colitis. |
| M30795 | INF4E | INF4E is a potent NLRP3 inflammasome inhibitor. INF4E inhibits caspase-1 and NLRP3 ATPase activities. INF4E shows protection against the IR-induced myocardial injury and dysfunction. |
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