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INF4E 

Cat. No. M30795

All AbMole products are for research use only, cannot be used for human consumption.

INF4E  Structure

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Quality Control & Documentation
Biological Activity

INF4E is a potent NLRP3 inflammasome inhibitor. INF4E inhibits caspase-1 and NLRP3 ATPase activities. INF4E shows protection against the IR-induced myocardial injury and dysfunction.

Chemical Information
Molecular Weight 240.68
Formula C12H13ClO3
CAS Number 88039-46-7
Form Liquid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuhua Shi, et al. Int Immunopharmacol. NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages

[2] Raffaella Mastrocola, et al. Oxid Med Cell Longev. Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways

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  Catalog
Abmole Inhibitor Catalog




Keywords: INF4E  supplier, NLR, inhibitors, activators

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