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BMS-986299 is a first-in-class (first-in-class) NLRP3 inflammatory vesicle agonist that induces IL8 release to activate natural killer (NK) cells with an EC50 of 1.28 μM.
| Molecular Weight | 349.39 |
| Formula | C18H19N7O |
| CAS Number | 2242952-69-6 |
| Solubility (25°C) | DMSO 70 mg/mL Water 17 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| NBC19
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