| Cat.No. | Name | Information |
|---|---|---|
| M1966 | Fulvestrant | Fulvestrant is a Estrogen receptor (ER) antagonist with IC50 of 0.094 nM. Fulvestrant can also induce autophagy and apoptosis, and has anti-tumor effect. |
| M3371 | Estriol | Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
| M4368 | Kaempferol | Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research. |
| M7353 | Tamoxifen | Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. |
| M7871 | G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. |
| M4374 | Gypenoside-XVII | Gypenoside XVII is a novel phytoestrogens belonging to gypenosides, which can activate estrogen receptors. |
| M2174 | Calcitriol | Calcitriol is an Active metabolite of vitamin D3 that activates the vitamin D receptor. *The compound is unstable in solutions, freshly prepared is recommended |
| M5625 | Estradiol | Estradiol (17β-estradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (17β-estradiol) can be used to construct animal models of chronic non-bacterial prostatitis. |
| M4836 | G-1 | G-1 is a potent and selective GPR30 receptor agonist (Ki = 11 nM, EC50 = 2 nM). |
| M8508 | PHTPP | PHTPP is a selective estrogen receptor β (ERβ) full antagonist with 36-fold selectivity for ERβ over ERα. |
| M10254 | SAR439859 (Amcenestrant) | SAR439859 (Amcenestrant) is an orally active, nonsteroidal and selective degrader of estrogen receptor, it is also a potent antagonist of ER with EC50 of 0.2 nM for ERα degradation. |
| M10252 | 4-Hydroxytamoxifen | 4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). |
| M9967 | Methylpiperidino pyrazole | Methylpiperidino pyrazole (MPP) is an agonist for estrogen receptor α and lacks any ligand functionality with estrogen receptor (ER)β. |
| M9881 | Bisphenol A | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. |
| M9796 | Endoxifen E-isomer hydrochloride | Endoxifen E-isomer hydrochloride is a tamoxifen metabolite and potent Selective Estrogen Response Modifier (SERM). |
| M9196 | Elagolix sodium | Elagolix Soidum is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. |
| M8953 | GDC-0810 | GDC-0810 (Brilanestrant, ARN-81) is an orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM. |
| M8565 | Estetrol | Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver. |
| M8422 | Lasofoxifene tartrate | Lasofoxifene is an orally active and selective estrogen receptor modulator (SERM) that inhibits primary tumor growth and metastasis. It may be used in studies related to breast cancer and postmenopausal osteoporosis. |
| M7839 | (E/Z)-4-Hydroxytamoxifen | (E/Z)-4-Hydroxytamoxifen is the racemate of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen and a modulator of the estrogen receptor (ER). |
| M7493 | XCT 790 | XCT 790 is a potent, selective ERRα inverse agonist with an IC50 value of 0.37 μM and is inactive against ERRγ and estrogen receptors ERα and ERβ. |
| M7483 | WAY 200070 | WAY 200070 is a selective ERβ agonist. |
| M6717 | ERB 041 | ERB 041 is a potent and selective estrogen receptor β (ERβ) agonist, with IC50s of 5.4, 3.1, and 3.7 nM for ERβ in humans, rats, and mice, respectively.ERB 041 is more than 200 times more selective for ERβ than for ERα. In addition, ERB 041 inhibits the WNT/β-catenin signaling pathway and induces apoptosis in ovarian cancer cells. |
| M6710 | Endoxifen Z-isomer hydrochloride | Endoxifen Z-isomer hydrochloride is a Tamoxifen metabolite and a potent estrogen receptor (ER) antagonist that concentration-dependently inhibits hERG with an IC50 value of 1.6 μM. |
| M6165 | GSK 4716 | GSK 4716 is a selective agonist with estrogen-related receptors ERRβ and ERRγ. |
| M6083 | AZD9496 | AZD9496 is an oral estrogen receptor inhibitor that blocks the growth of ER-positive and ESR1 mutant breast tumours in preclinical models. |
| M6069 | β-Estradiol 17-acetate | β-Estradiol 17-acetate is a metabolite of estradiol. |
| M5917 | Raloxifene HCl | RaloxifeneHcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist. |
| M5765 | Megestrol Acetate | Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway. |
| M5698 | Hydroxyprogesterone caproate | Hydroxyprogesterone Caproate is a synthetic progesterone receptor (PR) agonist that binds and activates the nuclear progesterone receptor in the reproductive system and may be used in studies related to genitourinary disorders. |
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