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Methylpiperidino pyrazole

Cat. No. M9967

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Methylpiperidino pyrazole Structure
Synonym:

MPP

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10mg USD 375 1-2 Weeks
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Quality Control & Documentation
Biological Activity

Methylpiperidino pyrazole (MPP) is an agonist for estrogen receptor α and lacks any ligand functionality with estrogen receptor (ER)β. Methyl-piperidino-pyrazole promotes silibinin induced apoptosis in human breast cancer MCF-7 cells.

Chemical Information
Molecular Weight 469.6
Formula C29H31N3O3
CAS Number 289726-02-9
Solubility (25°C) DMSO 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hai-Bing Zhou, et al. Bioorg Med Chem Lett. Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity

[2] Angela M Davis, et al. Mol Reprod Dev. The effects of the selective estrogen receptor modulators, methyl-piperidino-pyrazole (MPP), and raloxifene in normal and cancerous endometrial cell lines and in the murine uterus

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Keywords: Methylpiperidino pyrazole, MPP supplier, Estrogen Receptor, inhibitors, activators

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