| Cat.No. | Name | Information |
|---|---|---|
| M1966 | Fulvestrant | Fulvestrant is a Estrogen receptor (ER) antagonist with IC50 of 0.094 nM. Fulvestrant can also induce autophagy and apoptosis, and has anti-tumor effect. |
| M3371 | Estriol | Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
| M4368 | Kaempferol | Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research. |
| M7353 | Tamoxifen | Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. |
| M7871 | G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. |
| M4374 | Gypenoside-XVII | Gypenoside XVII is a novel phytoestrogens belonging to gypenosides, which can activate estrogen receptors. |
| M2174 | Calcitriol | Calcitriol is an Active metabolite of vitamin D3 that activates the vitamin D receptor. *The compound is unstable in solutions, freshly prepared is recommended |
| M4836 | G-1 | G-1 is a potent and selective GPR30 receptor agonist (Ki = 11 nM, EC50 = 2 nM). |
| M8508 | PHTPP | PHTPP is a selective estrogen receptor β (ERβ) full antagonist with 36-fold selectivity for ERβ over ERα. |
| M10348 | 27-Hydroxycholesterol | 27-Hydroxycholesterol is a selective estrogen receptor modulator, and it is also an agonist of the liver X receptor. |
| M14629 | Elacestrant dihydrochloride | Elacestrant dihydrochloride (RAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. |
| M14628 | Elacestrant | Elacestrant (RAD1901) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. |
| M14626 | Coumestrol | Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM. |
| M11268 | LSZ-102 | Lsz-102 is a potent, oral bioeffective selective estrogen receptor inhibitor with an IC50 value of 0.2 nM. |
| M11267 | Camizestrant | Camizestrant (AZD-9833) is an effective oral antagonist of the active estrogen receptor (ER). Camizestrant can be used in the study of ER+ HER2- breast cancer. |
| M10923 | Giredestrant | Giredestrant (GDC-9545, RG6171) is an orally active, selective estrogen receptor degrader (SERD) with best-in-class potential to compete with estradiol in the ER ligand binding domain and induce conformational changes.Giredestrant has antitumor activity. |
| M10555 | 17α-Estradiol | 17 alpha-Estradiol is a 5α-reductase inhibitor, and it inhibits testosterone metabolism catalyzed by 5 alpha-reductase. |
| M10348 | 27-Hydroxycholesterol | 27-Hydroxycholesterol is a selective estrogen receptor modulator, and it is also an agonist of the liver X receptor. |
| M10254 | SAR439859 (Amcenestrant) | SAR439859 (Amcenestrant) is an orally active, nonsteroidal and selective degrader of estrogen receptor, it is also a potent antagonist of ER with EC50 of 0.2 nM for ERα degradation. |
| M10252 | 4-Hydroxytamoxifen | 4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). |
| M9967 | Methylpiperidino pyrazole | Methylpiperidino pyrazole (MPP) is an agonist for estrogen receptor α and lacks any ligand functionality with estrogen receptor (ER)β. |
| M9881 | Bisphenol A | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. |
| M9796 | Endoxifen E-isomer hydrochloride | Endoxifen E-isomer hydrochloride is a tamoxifen metabolite and potent Selective Estrogen Response Modifier (SERM). |
| M9196 | Elagolix sodium | Elagolix Soidum is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. |
| M8953 | GDC-0810 | GDC-0810 (Brilanestrant, ARN-81) is an orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM. |
| M8565 | Estetrol | Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver. |
| M8508 | PHTPP | PHTPP is a selective estrogen receptor β (ERβ) full antagonist with 36-fold selectivity for ERβ over ERα. |
| M8422 | Lasofoxifene tartrate | Lasofoxifene is an orally active and selective estrogen receptor modulator (SERM) that inhibits primary tumor growth and metastasis. It may be used in studies related to breast cancer and postmenopausal osteoporosis. |
| M7839 | (E/Z)-4-Hydroxytamoxifen | (E/Z)-4-Hydroxytamoxifen is the racemate of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen and a modulator of the estrogen receptor (ER). |
| M7493 | XCT 790 | XCT 790 is a potent, selective ERRα inverse agonist with an IC50 value of 0.37 μM and is inactive against ERRγ and estrogen receptors ERα and ERβ. |
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