| Cat.No. | Name | Information |
|---|---|---|
| M1966 | Fulvestrant | Fulvestrant is a Estrogen receptor (ER) antagonist with IC50 of 0.094 nM. Fulvestrant can also induce autophagy and apoptosis, and has anti-tumor effect. |
| M3371 | Estriol | Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
| M4368 | Kaempferol | Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research. |
| M7353 | Tamoxifen | Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. |
| M7871 | G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. |
| M4374 | Gypenoside-XVII | Gypenoside XVII is a novel phytoestrogens belonging to gypenosides, which can activate estrogen receptors. |
| M2174 | Calcitriol | Calcitriol is an Active metabolite of vitamin D3 that activates the vitamin D receptor. *The compound is unstable in solutions, freshly prepared is recommended |
| M5625 | Estradiol | Estradiol (17β-estradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (17β-estradiol) can be used to construct animal models of chronic non-bacterial prostatitis. |
| M4836 | G-1 | G-1 is a potent and selective GPR30 receptor agonist (Ki = 11 nM, EC50 = 2 nM). |
| M8508 | PHTPP | PHTPP is a selective estrogen receptor β (ERβ) full antagonist with 36-fold selectivity for ERβ over ERα. |
| M3564 | Clomifene citrate | Clomifene citrate is a selective estrogen receptor modulator. |
| M3392 | Ethinyl Estradiol | Ethinyl Estradiol (Ethinylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. |
| M3333 | Hexestrol | Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively. |
| M3251 | Bazedoxifene Acetate | Bazedoxifene Acetate is a third generation, oral and nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. |
| M2684 | Estradiol Cypionate | Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor. |
| M2678 | Equol | Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. |
| M2516 | Cholesterol | Cholesterol is a major sterol in mammals, accounting for 20-25% of the structural components of the plasma membrane, and plays an important role in characterizing membrane fluidity and permeability, as well as the function of transporter and signaling proteins. In addition, Cholesterol is an endogenous estrogen-related receptor alpha (ERRα) agonist. |
| M2437 | Bazedoxifene hydrochloride | Bazedoxifene hydrochloride is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM. |
| M2280 | Tamoxifen Citrate (ICI 46474) | Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding. |
| M2097 | LY500307 | LY500307 is a potent, selective estrogen receptor beta agonist with an EC50 of 0.66 nM. |
| M57250 | AC-186 | AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. |
| M57249 | Idoxifene | Idoxifene (CB7432) is a novel tissue-specific selective estrogen receptor modulator (SERM). |
| M57248 | (R)-Equol | (R)-Equol is an agonist of both ERα and ERβ with Kis of 27.4 and 15.4 nM, respectively. |
| M57247 | (Rac)-Vepdegestrant | (Rac)-Vepdegestrant is the isomer of Vepdegestrant. |
| M57245 | Raloxifene 4'-glucuronide | Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. |
| M57244 | Giredestrant tartrate | Giredestrant tartrate (GDC-9545 tartrate), a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist. |
| M50377 | Yp537 | Yp537 is an estrogen receptor (ER) inhibitor that blocks dimerization of the human estrogen receptor. |
| M45361 | Palazestrant | Palazestrant is a novel, orally active, estrogen receptor antagonist and selective estrogen receptor degrader. It can be used in studies related to ER+/HER2+ breast cancer. |
| M45336 | Acolbifene hydrochloride | Acolbifene hydrochloride is an active metabolite of EM800 and an orally available, selective estrogen receptor modulator (SERM) that inhibits estradiol-induced ERα (IC50 = 2 nM) and ERβ (IC50 = 0.4 nM) transcriptional activity, has significant anti-estrogenic effects on the mammary gland and uterus, and has anticancer activity. possesses anticancer activity. |
| M45335 | Acolbifene | Acolbifene is an active metabolite of EM800 and an orally active pure anti-estrogen and selective estrogen receptor (ER) antagonist that inhibits estradiol-induced ERα (IC50 = 2 nM) and ERβ (IC50 = 0.4 nM) transcriptional activity and has anticancer activity. |
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