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Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives. It is a biologically inactive prodrug of ethinylestradiol to which it is demethylated in the liver with a conversion efficiency of 70% (50 ug of mestranol is pharmacokinetically bioequivalent to 35 ug of ethinylestradiol). </
| Molecular Weight | 310.43 |
| Formula | C21H26O2 |
| CAS Number | 72-33-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 10 mg/mL Ethanol 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Estrogen Receptor Products |
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| Idoxifene
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| (R)-Equol
(R)-Equol is an agonist of both ERα and ERβ with Kis of 27.4 and 15.4 nM, respectively. |
| (Rac)-Vepdegestrant
(Rac)-Vepdegestrant is the isomer of Vepdegestrant. |
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