| Cat.No. | Name | Information |
|---|---|---|
| M3143 | Z-VAD-FMK | Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor which blocks all features of apoptosis. |
| M2972 | Q-VD-OPh | Q-VD-OPh is a potent, irreversible pan-caspase inhibitor with IC50 ranging from 25 to 400 nM for caspases 1, 3, 8, and 9, showing inhibitory effects on terminal caspase activation, substrate cleavage, and DNA ladder formation associated with apoptosis. |
| M3134 | Z-DEVD-FMK | Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor with an IC50 of 18 μM, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. |
| M6233 | Z-YVAD-FMK | Z-YVAD-FMK is a synthetic peptide that irreversibly inhibits activity of caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. |
| M2403 | Apoptosis Activator 2 | Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. |
| M53407 | Z-VEID-FMK | Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. |
| M53406 | Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone | Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. |
| M53405 | Ac-AAVALLPAVLLALLAP-DEVD-CHO | Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) is a potent and reversible caspase-3 inhibitor. |
| M53404 | Ac-AAVALLPAVLLALLAP-LEHD-CHO | Ac-AAVALLPAVLLALLAP-LEHD-CHO is an inhibitor of caspases 4, 5 and 9. |
| M53403 | Ac-AAVALLPAVLLALLAP-LEVD-CHO | Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable caspase-4 inhibitor that has antitumor activity. |
| M53402 | Ac-AAVALLPAVLLALLAP-YVAD-CHO | Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity. |
| M53401 | Ac-Trp-Glu-His-Asp-Aldehyde | Ac-Trp-Glu-His-Asp-Aldehyde is a potent and selective caspase-1 inhibitor with a Ki value of 56 pM. |
| M53400 | Ac-Tyr-Val-Lys-Asp-aldehyde | Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia. |
| M53399 | Ac-Trp-Glu-His-Asp-AMC | Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1. |
| M53398 | Mca-YVADAP-Lys(Dnp)-OH | Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2). |
| M53397 | Mca-DEVDAP-K(Dnp)-OH | Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3. |
| M53396 | Z-LE(OMe)TD(OMe)-FMK | Z-LE(OMe)TD(OMe)-FMK is a selective caspase-8 inhibitor. |
| M53395 | Boc-Ala-Ala-Asp-pNA | Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. |
| M53394 | Z-Ala-Ala-Asp-CMK | Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. |
| M53393 | Biotin-DEVD-CHO | Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage. |
| M53392 | Tripeptide-32 | Tripeptide-32isa bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient. |
| M53391 | Ac-VDVAD-pNA | Ac-VDVAD-pNA is a caspase-2 substrate. |
| M53390 | Boc-AEVD-CHO | Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases. |
| M53389 | Ac-DEVD-CMK | Ac-DEVD-CMK (Caspase-3 Inhibitor III) is a selective and irreversible caspase-3 inhibitor. |
| M53388 | Ac-DMQD-AMC | Ac-DMQD-AMC is an inhibitor of caspase-3. |
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