| Cat.No. | Name | Information |
|---|---|---|
| M3143 | Z-VAD-FMK | Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor which blocks all features of apoptosis. |
| M2972 | Q-VD-OPh | Q-VD-OPh is a potent, irreversible pan-caspase inhibitor with IC50 ranging from 25 to 400 nM for caspases 1, 3, 8, and 9, showing inhibitory effects on terminal caspase activation, substrate cleavage, and DNA ladder formation associated with apoptosis. |
| M3134 | Z-DEVD-FMK | Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor with an IC50 of 18 μM, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. |
| M6233 | Z-YVAD-FMK | Z-YVAD-FMK is a synthetic peptide that irreversibly inhibits activity of caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. |
| M2403 | Apoptosis Activator 2 | Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. |
| M53387 | Ac-DNLD-CHO | Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively). |
| M53386 | Ac-LEVD-CHO | Ac-LEVD-CHO is a caspase-4 inhibitor. |
| M53385 | Ac-VETD-AMC | Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. |
| M53384 | Ac-VRPR-AMC | Ac-VRPR-AMC is a fluorogenic metacaspase substrate. |
| M53383 | Ac-YVAD-AOM | Ac-YVAD-AOM is the inhibitor of caspase-1 that shows antitumor activity. |
| M53382 | Ac-VAD-CHO | Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. |
| M53381 | Ac-VAD-pNA | Ac-VAD-pNA is a caspase-1 substrate. |
| M53380 | Z-IETD-pNA | Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. |
| M53379 | Z-VEID-AFC | Z-VEID-AFC is a fluorescent substrate for caspase-6. |
| M53378 | Z-YVAD-CMK | Z-YVAD-CMK is a caspase-1 and caspase-3 inhibitor. |
| M53377 | Z-YVAD-pNA | Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate. |
| M53376 | Z-VAD-AMC | Z-VAD-AMC is a substrate of caspase-9. |
| M53375 | TRP-601 | TRP-601 is a caspase inhibitor. |
| M53374 | GPR | GPR is a three amino acid peptide. |
| M49832 | Procaspase-3/6 activator 1 | Procaspase-3/6 activator 1 is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. |
| M45314 | Ac-ESMD-CHO | Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7 that inhibits the proteolytic cleavage of caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site. |
| M45309 | Ac-VDVAD-CHO | Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46/15 nM). |
| M41333 | IETD-CHO | IETD-CHO (Caspase-8-IN-1) is a potent caspase-8 inhibitor. |
| M41332 | IETD-CHO TFA | IETD-CHO TFA (Caspase-8-IN-1) is a potent caspase-8 inhibitor. |
| M41331 | Ac-DEVD-CMK TFA | Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible caspase-3 inhibitor. |
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