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Apoptosis Apoptosis related

Cat.No.  Name Information
M9075 Etomoxir sodium salt Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
M10566 Valepotriate Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M7755 Dehydroleucodine Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers.
M38844 Glyphosate Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants.
M4492 Curcurbitacin-Iib Cucurbitacin IIb is the active ingredient in chorioides, which induces apoptosis and has anti-inflammatory activity. Cuc
M4490 Protosappanin-B Protosappanin B is a polyphenol substance extracted from Sappanwood, which has anti-tumor effect. In human bladder cancer cells, it can induce apoptosis by arresting G1 phase of cell cycle.
M4489 Brazilin Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities.
M4477 Costunlide Costunlide
M4471 Loganin Loganin, the main iridoid glycoside in cornus officinalis, has anti-inflammatory and anti-shock effects.
M4462 Oroxin-B Oroxin B (OB) is a flavonoid isolated from the traditional Chinese herb Oroxylum indicum (L.) Vent. Oroxin B (OB) can inhibit hepatoma cells by up-regulating PTEN, down-regulating COX-2, VEGF, PI3K and P-Akt, and induce early apoptosis. Oroxin B (OB) induces suppressive ER stress in malignant lymphoma cells.
M4434 Isoalantolactone Isoalantolactone is an alkylating agent used as an apoptosis inducer.
M4432 Columbianadin Columbianadin is a natural coumarin from Angelica Decursiva (Umbelliferae) and is known to have a variety of biological activities, including anti-inflammatory and anticancer effects.
M4429 Levistilide A Levistilide A (Levistolide A) is a natural compound isolated from the traditional Chinese medicine Ligusticum chuanxiong and used to study cancer. Levistilide A (Levistolide A) induces apoptosis through ENDOplasmic reticulum stress mediated by ROS.
M4424 Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) is an alkyl pyrazine extracted from Ligusticum wallichii (Chuan Xiong), often used as a flavor in French fries, bread, tea, dairy products, bean products and other food. Ligustrazine has potential antineural and anti-inflammatory activities in rats.
M4405 Obacunone Obacunone is isolated from swamp white grapefruit seeds and plays an anticancer role by inducing apoptosis.
M4396 Fraxetin Fraxetin is separate from Cortex Fraxini. Fraxetin has anti-tumor, antioxidant and anti-inflammatory effects. Fraxetin can induce apoptosis.
M4387 Carnosic-acid Carnosic acid inhibits oxidative stress and inflammation, inhibits cell proliferation, and has antibacterial activity.
M4380 Curcumol Curcumol ((-) -curcumol) is a bioactive sesquiterpene with many pharmacological activities, such as anti-cancer, anti-microbial, anti-fungal, antiviral and anti-inflammatory. Curcumol can effectively induce apoptosis in many cancer cells by targeting key signaling pathways such as MAPK/ERK, PI3K/Akt and NF-κB, which are often abnormally regulated in several cancers.
M4375 Hypericin Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect.
M4362 Polyphyllin-II Polyphyllin II is one of the most important saponins in Polyphyllin, which has toxic effects on a variety of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell cycle arrest.
M4358 Caudatin Caudatin is a steroid substance in Polygonum multiflorum, which can inhibit cell cycle and induce apoptosis, and has anti-tumor and anti-angiogenesis effects.
M4331 Paederosidic-acid Paederosidic acid, isolated from P. scandens, has anticancer and anti-inflammatory activities. Paederosidic acid inhibits lung cancer cells by inducing mitochondria - mediated apoptosis.
M4315 Lucidenic-acid-B Lucidenic acid B is a natural product isolated from Ganoderma lucidum, which can induce tumor cell apoptosis, activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B had no effect on cell cycle and no effect on necrotic cells.
M4307 Ganoderenic-acid-D Ganoderenic acid D is a reishi extract (GLE), triterpenoids. Ganoderenic acid D inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis apoptosis.




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