| Cat.No. | Name | Information |
|---|---|---|
| M4429 | Levistilide A | Levistilide A (Levistolide A) is a natural compound isolated from the traditional Chinese medicine Ligusticum chuanxiong and used to study cancer. Levistilide A (Levistolide A) induces apoptosis through ENDOplasmic reticulum stress mediated by ROS. |
| M4428 | Senkyunolide-I | Senkyunolide I can be isolated from Ligusticum chuanxiong Hort and is an antimigraine compound. Senkyunolide I protects rat brain from focal cerebral ischemia-perfusion injury by up-regulating P-ERK1/2, Nrf2/HO-1 and inhibiting Caspase 3. |
| M4427 | Senkyunolide-A | Senkyunolide-A is one of the main active ingredients of Ligusticum chuanxiong, A compound commonly used in the study of cardiovascular diseases. It has antitumor activity. |
| M4426 | Senkyunolide-H | Senkyunolide H is a natural compound extracted from Ligusticum chuanxiong Hort. |
| M4425 | 3-Butylidenephthalide | 3-butylidenephthalide (i.e. 3-butylidenephthalide) is a phthalic anhydride derivative identified from Ligusticum chuanxiong Hort. It has insecticidal activity (LC50 value of 1.56 mg/g for Spodoptera Litura Spodoptera). |
| M4424 | Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) | Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) is an alkyl pyrazine extracted from Ligusticum wallichii (Chuan Xiong), often used as a flavor in French fries, bread, tea, dairy products, bean products and other food. Ligustrazine has potential antineural and anti-inflammatory activities in rats. |
| M4423 | Sennidin-B | Sennidin B can be isolated from Cassia Angustifolia and is an isomer of Sennidin A with lower activity than Sennidin A. Sennidin A inhibited HCV NS3 helicase with an IC50 value of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4). Sennidin A stimulates glucose incorporation. |
| M4422 | Sennidin-A | Sennidin A was isolated from Cassia Angustifolia and inhibited HCV NS3 helicase with an IC50 value of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4). Sennidin A stimulates glucose incorporation. |
| M4421 | Sennoside-D | Sennoside D is an anthraquinone glycoside found in the leaves and pods of senna (Cassia Angustifolia). |
| M4420 | Sennoside-C | Sennoside C is an anthraquinone glycoside found in the leaves and pods of senna (Cassia Angustifolia). |
| M4419 | Sennoside-B | Sennoside B is an anthraquinone glycoside found in abundance in the leaves and pods of senna (Cassia Angustifolia). Sennoside B inhibits PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and down-regulating the PDGFR-β signaling pathway. |
| M4418 | Sennoside-A | Sennoside A is an anthraquinone glycoside found in abundance in the leaves and pods of senna (Cassia Angustifolia). Sennoside A is an HIV-1 inhibitor that inhibits HIV-1 replication. |
| M4417 | 7-Epitaxol | 7-Epi-Taxol is the active metabolite of Taxol, which has similar effects to Taxol in inhibiting cell proliferation, microtubule dissociation and inducing microtubule polymerization. |
| M4416 | Cephalomannine | Cephalomannine is a taxol alkaloid analogue that can be isolated from most tricuspid taxus species. Cephalomannine is an orally active anti-tumor agent that can be used as a chemotherapy agent for cancer research. |
| M4415 | Sesamolin | Sesaminol can be isolated from Justicia Orbiculata and has antioxidant activity. Sesaminol inhibits lipid peroxidation and has neuroprotective effect. Sesaminol inhibits MAPK cascade by inhibiting phosphorylation of JNK, P38 MAPKs, and Caspase-3. |
| M4414 | Gentiopicrin | Gentiopicroside is a natural iridoid glycoside that can inhibit the activity of P450 with IC50 and Ki values of 61 µM and 22.8 µM for CYP2A6, respectively. Gentiopicroside has anti-inflammatory and antioxidant activities. |
| M4413 | Picroside-III | Picroside III is a iridoid glycoside isolated from Picrorhiza Scrophulariiflora (PS), a traditional Chinese medicine. |
| M4412 | Picroside-II | Picroside II lutein II is a iridoid compound extracted from Lutein, which has anti-inflammatory and anti-apoptotic effects. |
| M4411 | Picroside-I | Picroside I (6' -cinnamoylcatalpol) is a major ingredient of Picrorhiza Kurroa. Picrorhiza Kurroa is a high value medicinal plant rich in liver-protecting metabolites Picroside I and Picroside-II. Picroside I could be used in asthma studies. Picroside I significantly reduces inflammation. Picroside I also down-regulated pSTAT6 and GATA3 expression. Picroside I dose-dependently increases serum IFN-γ levels. |
| M4410 | Coptisine-Sulfate | Coptisine Sulfate is an alkaloid isolated from coptis coptidis. It is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. |
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