| Cat.No. | Name | Information |
|---|---|---|
| M4522 | Ursolic acid | Ursolic acid (Prunol) is a natural triterpenoid carboxylic acid compound with preventive and anticancer activities. Ursolic acid also has proteasome agonist activity, EC50=14 μmol/L. |
| M4521 | Dehydrocorydaline | Dehydrocorydaline is an alkaloid, it can regulate protein expression of Bax, Bcl-2. Dehydrocorydaline elevates p38 MAPK activation. Dehydrocorydaline elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline shows strong anti-malarial effects, and low cytotoxicity. |
| M4520 | (+)-Corydaline | Corydaline ((+) -corydaline) is an isoquinoline alkaloid extracted from Corydalis Yanhusuo. It is an inhibitor of AChE with IC50 of 226 µM. Corydaline is a μ-opioid receptor agonist (Ki = 1.23 µM) that inhibits the replication of enterovirus 71 (EV71) (IC50 = 25.23 µM). Corydaline has anti-angiogenesis, anti-allergy, gastric emptying and anti-nociception effects. |
| M4519 | Procyanidin-B1 | Procyanidin B1 is a polyphenolic flavonoid that exists in common fruits and can bind to TLR4/MD-2 complex, showing anti-inflammatory activity. |
| M4518 | Procyanidin-B2 | Procyanidin B2 is a natural flavonoid with anti-tumor and anti-oxidation effects. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway. |
| M4517 | Proanthocyanidins | Proanthocyanidins can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties. |
| M4516 | Sinomenine-Hydrochloride | Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid derived from Sinomenium Acutum, is a blocker of NF-κB activation. Sinomenine is also a μ-opioid receptor activator. |
| M4515 | Fangchinoline | Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities. |
| M4514 | Tetrandrine | Tetrandrine (NSC-77037; D-tetrandrine) is a diphenylisoquinoline alkaloid that inhibits voltage-gated calcium channels (ICa) and Ca2+ -activated potassium channels. |
| M4513 | Dihydrocapsaicin | Dihydrocapsaicin is a natural capsaicin that is a selective TRPV1 agonist and increases P-Akt levels. Dihydrocapsaicin can enhance hypothermic induced neuroprotection. |
| M4512 | Tectoridin | Tectoridin is an isoflavone isolated from Maackia Amurensis. Tectoridin is a phytoestrogen that activates estrogen and thyroid hormone receptors. Tectoridin exerts estrogenic effects through the ER dependent genomic pathway and the GPR30 dependent non-genomic pathway. |
| M4511 | Tectorigenin | Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. |
| M4510 | Madecassic-acid | Madecassic acid was isolated from Centella asiatica (umbelliferae). Madecassic acid showed inhibition of iNOS, COX-2, TNF-α, IL-1beta and IL-6, and had anti-inflammatory effect by down-regulation of NF-κB activation in RAW 264.7 macrophages. |
| M4509 | Asiatic-acid | Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing. |
| M4508 | Madecassoside | Madecassoside is an anti-inflammatory pentacyclic triterpenoid isolated from a large bowl. Antioxidant and anti-aging effects. |
| M4507 | Scopolin | Scopolin is a coumarin isolated from the roots of Arabidopsis. Scopolin mitigated hepatic steatosis by activating sirT1-mediated signaling cascades. |
| M4506 | Morusin | Morusin is a prenylated flavonoid isolated from Morus alba Linn., which could inhibit NF-κB and STAT3 activity. Morusin has various biological activities, such as antitumor, antioxidant, and anti-bacteria property. |
| M4505 | Sanggenone-D | Sanggenon D is a Diels-Alder type adduct from the bark of Morus Cathayana. Sanggenon D showed antioxidant activity and inhibited pancreatic lipase (PL) with IC50 of 0.77 μM. |
| M4504 | Sanggenone-C | Sanggenon C is a flavanone diels-Alder adduct compound isolated from the root bark of the genus Morus Cathayana. |
| M4503 | Mulberroside-C | Mulberroside C is one of the main bioactive components in Mulberry (Morus alba L.). Mulberroside C inhibits HCV replication. It has antiviral activity. |
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