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Dehydrocorydaline is an alkaloid, it can regulate protein expression of Bax, Bcl-2. Dehydrocorydaline elevates p38 MAPK activation. Dehydrocorydaline significantly inhibits the growth of MCF-7 cells in a dose-dependent manner. Dehydrocorydaline (0-200 μM)dose-dependently increases Bax protein expression and decreases Bcl-2 protein expression.
| Molecular Weight | 366.43 |
| Formula | C22H24NO4+ |
| CAS Number | 30045-16-0 |
| Solubility (25°C) | DMSO 40 mg/mL Soluble in acidic solution |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Bcl-2 Products |
|---|
| ABBV-467
ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). |
| WEHI-539
WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM. |
| (Rac)-Lisaftoclax
(Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research. |
| BcI-2/BcI-xI ligand 1
BcI-2/BcI-xI ligand 1 is a BcI-2/BcI-xI ligand, and can be used for synthesis of PROTAC BcI-2/BcI-xI Degrader-1. |
| AZD-5991 (S-enantiomer)
AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. |
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