| Cat.No. | Name | Information |
|---|---|---|
| M4366 | Pseudoprotodioscin | Pseudoprotodioscin, a furan glucoside, inhibits sREBP1/2 and microRNA 33A/B levels and reduces the expression of genes associated with cholesterol and triglyceride synthesis. |
| M4365 | Protodioscin | Protodioscin |
| M4364 | Paris saponin VII | Paris saponin VII (Chonglou Saponin VII) is a steroid saponin isolated from the roots and rhizomes of Trillium tschonoskii Maxim. |
| M4363 | Polyphyllin-VI | Polyphyllin VI, an active saponin, has anticancer activity. Polyphyllin VI induces G2/M cell cycle arrest and induces apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis by inducing ROS/NF-κB/NLRP3/GSDMD signaling axis in non-small cell lung cancer. |
| M4362 | Polyphyllin-II | Polyphyllin II is one of the most important saponins in Polyphyllin, which has toxic effects on a variety of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell cycle arrest. |
| M4361 | Polyphyllin-I | Polyphyllin I is a bioactive ingredient extracted from Paris Polyphylla with strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis. |
| M4360 | Qingyangshengenin-B | Qingyangshengenin B C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against the toxicity of Aβ by decreasing the expression of Aβ at mRNA level. Qingyangshengenin B has antiepileptic activity. |
| M4359 | Qingyangshengenin-A | Qingyangshengenin A, A C-21 steroid isolated from Cynanchum otophyllum Schneid, has antiepileptic activity. |
| M4358 | Caudatin | Caudatin is a steroid substance in Polygonum multiflorum, which can inhibit cell cycle and induce apoptosis, and has anti-tumor and anti-angiogenesis effects. |
| M4357 | 3-Isomangostin | 3 - Isomangostin from Garciniamangostana. L. Extracted from shell, 3-isomangostin is an effective MutT homolog 1 (MTH1) inhibitor with IC50 value of 52 nM. 3-Isomangostin can be used to develop anticancer agents. |
| M4356 | β-Mangostin | Beta-mangostin (β -mangostin) is a compound of oxyxanthone present in Cratoxylum arborescens, which has antibacterial and antimalarial activities. The MIC value of beta-mangostin against M. tuberculosis was 6.25 μg/mL. Beta-mangostin showed anti-malarial activity in vitro with IC50 value of 3.00 μg/mL against P. falciparum. Beta-mangostin has strong anticancer activity against various cancers, such as hepatocellular carcinoma and leukemia. |
| M4355 | α-Mangostin | Alpha-mangostin is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. |
| M4354 | Cichoric-Acid | Cichoric Acid is a natural compound with antioxidant activity. |
| M4353 | Myrislignan | Myrislignan is a lignan isolated from Myristica Fragrans Houtt with anti-inflammatory activity. Myrislignan mitigated LPS-induced inflammation in mouse macrophages by inhibiting the activation of the NF-KB signaling pathway. |
| M4352 | (-)-Licarin-B | Licarin B, derived from the seed of Myristica Fragrans, is an inhibitor of NO production that improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway. |
| M4351 | Dehydrodiisoeugenol | Dehydrodiisoeugenol was isolated from Myristica Fragrans Houtt with anti-inflammatory and antibacterial effects. Dehydrodiisoeugenol inhibited NF-κB activation and cycde-2 gene expression in LPS-stimulated mouse macrophages. |
| M4350 | Vincristine | Vincristine |
| M4349 | Catharanthine-hemitartrate | Catharanthine Tartrate is an alkaloid found in periwinces that inhibits voltage-gated L-type Ca2+ channels in a function-operated cell and has anti-tumor and blood pressure lowering activities. |
| M4347 | Vinblastine | Vinblastine |
| M4346 | Vindoline | Vindoline is a Catharanthus roseus alkaloid that has a weak inhibitory effect on the self-assembly of tubulin. |
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