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2-acetylacteoside

Cat. No. M4454
2-acetylacteoside Structure
Size Price Availability Quantity
5mg USD 175  USD175 In stock
10mg USD 300  USD300 In stock
20mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

2' -acetylacteoside (2' -acetylacteoside) is a kind of phenylethanol glycoside isolated from Phyllostachys chinensis, which can inhibit erythrocyte hemolysis induced by free radicals and has scavenging activity.

Chemical Information
Molecular Weight 666.62
Formula C31H38O16
CAS Number 94492-24-7
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Wei Gao, et al. Effects of phenylethanol glycosides from Orobanche cernua Loefling on UVB-Induced skin photodamage: a comparative study

[2] Yanting Li, et al. Beneficial effect of 2'-acetylacteoside on ovariectomized mice via modulating the function of bone resorption

[3] Ke Zhang, et al. Chemome profiling and comparison of three Orobanche medicinal plants

[4] Xiaoming Wang, et al. An Integrated Approach to Characterize Intestinal Metabolites of Four Phenylethanoid Glycosides and Intestinal Microbe-Mediated Antioxidant Activity Evaluation In Vitro Using UHPLC-Q-Exactive High-Resolution Mass Spectrometry and a 1,1-Diphenyl-2-picrylhy䲧畸Ỵ畹㧀畷羹皖

[5] Xiaoming Wang, et al. Comparison of the Chemical Profiles and Antioxidant Activities of Different Parts of Cultivated Cistanche deserticola Using Ultra Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry and a 1,1-Diphenyl-2-picrylhydrazyl-Based Assay

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Keywords: 2-acetylacteoside supplier, inhibitors, activators


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