| Cat.No. | Name | Information |
|---|---|---|
| M4376 | Forsythin | Phillyrin (Forsythin) is isolated from forsythia and has antibacterial and anti-inflammatory properties. Phillyrin can potentially induce CYP1A2 and CYP2D1 in rats, but does not affect THE activities of CYP2C11 and CYP3A1/2. Phillyrin has activity against influenza A virus. |
| M4375 | Hypericin | Hypericin is an extract of Hypericum perforatum, which has strong antiviral effect and anti-tumor effect. |
| M4373 | Gypenoside-A | Gypenoside-A is a natural product isolated from Gynostemma pentaphyllum, has anti-cancer, hypoglycemic, hypolipidemic, immune enhancement effects, etc. |
| M4372 | Gypenoside XLIX | Gypenoside XLIX is a dammarane-type glycoside, the main constituent of G. pentaphyllum. Gypenoside XLIX is a selective PPAR-α activator that inhibits cytokine-induced VCAM-1 overexpression in human endothelial cells and hyperactive. |
| M4371 | N-Methylcytisine | N-methylcytisine (Caulophylline) is a tricyclic quinoline alkaloid with hypoglycemic, pain-relieving and anti-inflammatory activities. N-methylcytisine is a selective ligand of the acetylcholine acetylcholine receptor in the central nervous system and has a high affinity for the acetylcholine acetylcholine receptor in the optic ganglion of squid (Kd: 50 nM). |
| M4370 | Trifolirhizin | Trifolirhizin is a pterocarpan flavonoid isolated from the root of Sophora flavescoreae. Trifolirhizin showed high tyrosinase inhibitory activity with IC50 of 506 μM. Trifolirhizin has potential anti-inflammatory and anticancer activities. |
| M4369 | Kaempferide | Kaempferide is an O-methylated flavonol also found in kaempferia galanga. Kaempferide has antiviral activity. |
| M4367 | Xanthotoxol | Xanthotoxol (8-hydroxypsoralen) is a bioactive linear furan coumarin with strong pharmacological activities such as anti-inflammatory, antioxidant, 5-HT antagonist and neuroprotective effects. |
| M4366 | Pseudoprotodioscin | Pseudoprotodioscin, a furan glucoside, inhibits sREBP1/2 and microRNA 33A/B levels and reduces the expression of genes associated with cholesterol and triglyceride synthesis. |
| M4365 | Protodioscin | Protodioscin |
| M4364 | Paris saponin VII | Paris saponin VII (Chonglou Saponin VII) is a steroid saponin isolated from the roots and rhizomes of Trillium tschonoskii Maxim. |
| M4363 | Polyphyllin-VI | Polyphyllin VI, an active saponin, has anticancer activity. Polyphyllin VI induces G2/M cell cycle arrest and induces apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis by inducing ROS/NF-κB/NLRP3/GSDMD signaling axis in non-small cell lung cancer. |
| M4362 | Polyphyllin-II | Polyphyllin II is one of the most important saponins in Polyphyllin, which has toxic effects on a variety of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell cycle arrest. |
| M4361 | Polyphyllin-I | Polyphyllin I is a bioactive ingredient extracted from Paris Polyphylla with strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis. |
| M4360 | Qingyangshengenin-B | Qingyangshengenin B C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against the toxicity of Aβ by decreasing the expression of Aβ at mRNA level. Qingyangshengenin B has antiepileptic activity. |
| M4359 | Qingyangshengenin-A | Qingyangshengenin A, A C-21 steroid isolated from Cynanchum otophyllum Schneid, has antiepileptic activity. |
| M4358 | Caudatin | Caudatin is a steroid substance in Polygonum multiflorum, which can inhibit cell cycle and induce apoptosis, and has anti-tumor and anti-angiogenesis effects. |
| M4357 | 3-Isomangostin | 3 - Isomangostin from Garciniamangostana. L. Extracted from shell, 3-isomangostin is an effective MutT homolog 1 (MTH1) inhibitor with IC50 value of 52 nM. 3-Isomangostin can be used to develop anticancer agents. |
| M4356 | β-Mangostin | Beta-mangostin (β -mangostin) is a compound of oxyxanthone present in Cratoxylum arborescens, which has antibacterial and antimalarial activities. The MIC value of beta-mangostin against M. tuberculosis was 6.25 μg/mL. Beta-mangostin showed anti-malarial activity in vitro with IC50 value of 3.00 μg/mL against P. falciparum. Beta-mangostin has strong anticancer activity against various cancers, such as hepatocellular carcinoma and leukemia. |
| M4355 | α-Mangostin | Alpha-mangostin is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. |
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