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Gypenoside XLIX

Cat. No. M4372

All AbMole products are for research use only, cannot be used for human consumption.

Gypenoside XLIX Structure
Size Price Availability Quantity
5mg USD 59 In stock
10mg USD 99 In stock
20mg USD 159 In stock
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Quality Control & Documentation
Biological Activity

Gypenoside XLIX is a dammarane-type glycoside, the main constituent of G. pentaphyllum. Gypenoside XLIX is a selective PPAR-α activator that inhibits cytokine-induced VCAM-1 overexpression in human endothelial cells and hyperactive. Gynostemma saponin XLIX has many effects such as lowering blood pressure, lowering blood lipids, enhancing immunity, anti-arteriosclerosis and inhibition of thrombosis.

Chemical Information
Molecular Weight 1047.23
Formula C52H86O21
CAS Number 94987-08-3
Form Solid
Solubility (25°C) DMSO
Storage 2-8°C, protect from light, sealed
References

[1] Qixia Liu, et al. Gypenoside XLIX loaded nanoparticles targeting therapy for renal fibrosis and its mechanism

[2] Qin Yang, et al. Gypenoside XLIX protects against acute kidney injury by suppressing IGFBP7/IGF1R-mediated programmed cell death and inflammation

[3] Tom Hsun-Wei Huang, et al. Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells

[4] Tom Hsun-Wei Huang, et al. Gypenoside XLIX, a naturally occurring gynosaponin, PPAR-alpha dependently inhibits LPS-induced tissue factor expression and activity in human THP-1 monocytic cells

[5] Tom Hsun-Wei Huang, et al. Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway

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Keywords: Gypenoside XLIX supplier, PPAR, inhibitors, activators

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