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Gypenoside XLIX

Cat. No. M4372

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Gypenoside XLIX Structure
Size Price Availability Quantity
5mg USD 78  USD78 In stock
10mg USD 132  USD132 In stock
20mg USD 210  USD210 In stock
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Quality Control & Documentation
Biological Activity

Gypenoside XLIX is a dammarane-type glycoside, the main constituent of G. pentaphyllum. Gypenoside XLIX is a selective PPAR-α activator that inhibits cytokine-induced VCAM-1 overexpression in human endothelial cells and hyperactive. Gynostemma saponin XLIX has many effects such as lowering blood pressure, lowering blood lipids, enhancing immunity, anti-arteriosclerosis and inhibition of thrombosis.

Chemical Information
Molecular Weight 1047.23
Formula C52H86O21
CAS Number 94987-08-3
Form Solid
Solubility (25°C) DMSO
Storage 2-8°C, protect from light, sealed
References

[1] Qixia Liu, et al. Gypenoside XLIX loaded nanoparticles targeting therapy for renal fibrosis and its mechanism

[2] Qin Yang, et al. Gypenoside XLIX protects against acute kidney injury by suppressing IGFBP7/IGF1R-mediated programmed cell death and inflammation

[3] Tom Hsun-Wei Huang, et al. Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells

[4] Tom Hsun-Wei Huang, et al. Gypenoside XLIX, a naturally occurring gynosaponin, PPAR-alpha dependently inhibits LPS-induced tissue factor expression and activity in human THP-1 monocytic cells

[5] Tom Hsun-Wei Huang, et al. Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway

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Keywords: Gypenoside XLIX supplier, PPAR, inhibitors, activators

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