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Forsythin

Cat. No. M4376

All AbMole products are for research use only, cannot be used for human consumption.

Forsythin Structure
Synonym:

Phillyrin

Size Price Availability Quantity
5mg USD 45  USD45 In stock
10mg USD 75  USD75 In stock
20mg USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Phillyrin (Forsythin) is isolated from forsythia and has antibacterial and anti-inflammatory properties. Phillyrin (Forsythin) can potentially induce CYP1A2 and CYP2D1 in rats, but does not affect THE activities of CYP2C11 and CYP3A1/2. Phillyrin (Forsythin) has activity against influenza A virus.

Chemical Information
Molecular Weight 534.55
Formula C27H34O11
CAS Number 487-41-2
Solubility (25°C) DMSO ≥ 200 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zhong Han, et al. Genetic Toxicology and Safety Pharmacological Evaluation of Forsythin

[2] Lu-Lu Pan, et al. Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry

[3] Lu-Lu Pan, et al. Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified

[4] Zhaoyi Wang, et al. Phytochemistry, pharmacology, quality control and future research of Forsythia suspensa (Thunb.) Vahl: A review

[5] Xiaolong Pan, et al. Forsythin inhibits lipopolysaccharide-induced inflammation by suppressing JAK-STAT and p38 MAPK signalings and ROS production

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Keywords: Forsythin, Phillyrin supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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