| Cat.No. | Name | Information |
|---|---|---|
| M4794 | Hispidulin | Hispidulin is a natural flavonoid with a wide range of biological activities. Hispidulin is an inhibitor of PIM-1 with IC50 value of 2.71 μM. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. |
| M4793 | Artemisetin | Artemitin is a natural flavonoid, which exists in hexagon pterygium, and has antioxidant, anti-inflammatory and antiviral effects. |
| M4792 | Sinapine-thiocyanate | Sinapine, an alkaloid derived from seeds of the cruciferous species, possess antioxidant and radio-protective activities, downregulats multi-drug resistance 1 (MDR1) expression. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor. |
| M4790 | β-demonic-acid | β-demonic-acid exhibits anti-inflammatory effects. |
| M4788 | Scopoletin | Scopoletin is an acetylcholinesterase (AChE) inhibitor. |
| M4787 | Euphorbia-factor-L1 | Euphorbia Factor L1, a diterpenoid compound, can reduce the protein and mRNA levels of Bcl-2, PI3K, AKT and mTOR, and up-regulate the protein levels of Caspase-9 and Caspase-3. There was no effect on caspase-9 and caspase-3 protease. Euphorbia Factor L1 can induce autophagy and has anti-cancer, anti-adipogenesis, anti-osteoclast formation and multiple drug resistance regulation effects. |
| M4786 | Aristolochic acid A | Aristolochic acid A (Aristolochic acid I; TR 1736) is the principal component of the plant extract Aristolochic Acids, found in Aristolochia and Asarum herbs. Aristolochic acid A significantly decreased activator protein 1 (AP-1) and NF-κB activity. Aristolochic acid A reduces the expression of bladder cancer-associated BLCAP gene in human cells. |
| M4785 | Pteryxin | Pteryxin, coumarin in the leaves of Pteryxin, has anti-obesity effect. Pteryxin is an effective butyrylcholinesterase (BChE) inhibitor with IC50 value of 12.96 μg/ mL |
| M4784 | Hordenine | Hordenine is an alkaloid found in plants that inhibits melanin production by inhibiting the production of cAMP. |
| M4783 | Diosimin | Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary. Diosimin is also an agonist of the aryl hydrocarbon receptor (AhR), capable of upregulating the expression of p53, caspase 3, and caspase 9 in A431 cells, while downregulating the levels of Bcl-2 and matrix metalloproteinases (MMP-2 and MMP-9). Its metabolite, diosmetin, inhibits 3H-dopamine uptake in a dose-dependent manner with an IC50 value of 4 μM. |
| M4782 | Bilirubin | Bilirubin is a yellow breakdown product of heme catabolism. |
| M4781 | Homovanillic-acid | Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency. |
| M4780 | 4-Demethylepipodophyllotoxin | 4 '- Demethylepipodophyllotoxin (4' - DMEP) is an intermediate compounds, can inhibit microtubule assembly. |
| M4778 | Apo-12’-lycopenal | Apo-12’-lycopenal |
| M4777 | Pregnenolone | Pregnenolone (3β -hydroxy-5-pregnen-20-one) is a powerful neurosteroid, and is the major precursor of various steroids, including steroids. Pregnenolone is a specific signaling inhibitor of cannabinoid CB1 receptor. |
| M4775 | Gambogic-acid | Gambogic Acid (beta-Guttiferrin) a Gambogic resin from the Garcinia Hanburyi tree. Gambogic Acid (beta-guttiferrin) inhibited bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and McL-1 with IC50 values of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, respectively. 1.06 μM and 0.79 μM. |
| M4774 | 11-hydroxy-sugiol | 11-hydroxy-sugiol |
| M4773 | Jatropholone-B | Jatropholone-B |
| M4772 | Berberine-Sulfate | Berberine-Sulfate |
| M4771 | Dihydroberberine | Dihydroberberine inhibited the human Ether-related gene (hERG) channel and significantly reduced the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine has anti-inflammatory, antiatherosclerotic, hylipidemic and antitumor activities. |
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