| Cat.No. | Name | Information |
|---|---|---|
| M4541 | Dehydroandrographolide | Dehydroandrographolide is extracted from the herb andrographolia andrographolide. Dehydroandrographolide reduces oxidative stress in LPS-induced acute lung injury by inactivating iNOS and has anti-infective activity. |
| M4540 | Scutellarein | Scutellarein is a natural flavonoid with anti-inflammatory effects. |
| M4539 | Polygalasaponin-F | Polygalasaponin F is an oleanane type triterpenoid saponin extracted from Polygala Japonica, which can reduce the release of inflammatory cytokine tumor necrosis factor α (TNFa). Polygalasaponin F reduces the secretion of neuroinflammatory cytokines by regulating the TLR4-PI3K/ Akt-NF-KB signaling pathway. |
| M4536 | Myricetrin | Myricitrin is a major antioxidant. |
| M4535 | Myricetin | Myricetin is a platelet activating factor (PAF) antagonist. |
| M4534 | Daurisoline | Daurisoline is an hERG inhibitor and also an autophagy inhibitor. |
| M4533 | Dauricine | Dauricine is a diphenylisoquinoline alkaloid isolated from Asiatic Moonseed Rhizome and has anti-inflammatory activity. Dauricine inhibited proliferation, invasion and apoptosis of colon cancer cells in a dose-dependent manner by inhibiting NF-κB activation. |
| M4532 | Rhodionin | Rhodionin was isolated from the roots of Rhodiola crenulata and is a specific non-competitive cytochrome P450 2D6 inhibitor with IC50 of 0.761 μM and Ki of 0.769 μM. Rhodionin effectively inhibited acetylcholinesterase (AChE) in a dose-dependent manner with an IC50 range of 57.50 to 2.43 μg/mL. Rhodionin had effective DPPH radical scavenging activity with IC50 of 19.49 μM. |
| M4531 | Rosiridin | Rosiridin inhibits MAO A and MAO B and has A potential role in depression and alzheimer's disease. The inhibition rate of Rosiridin against MAO B at 10 μM was 83.8% (pIC50=5.38). |
| M4530 | Rosin | Isolated from pine or pine piles, Rosin is a frequent contact allergen that causes allergic contact dermatitis. |
| M4529 | Rosavin | Rosavin comes from R. Rosea. Rosavin has shown antidepressant, adaptogenic and antianxiety - like effects in mouse models. |
| M4528 | Rosarin | Rosarin is a cinnamyl glycoside isolated from rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin inhibited the expression of iNOS, IL-1β and TNF-α in the kidney and prefrontal cortex of mice. |
| M4527 | Oxypaeoniflorin | Oxypaeoniflorin, a monoterpene glycoside isolated from Paeoniae, is an antioxidant. Oxypaeoniflorin has neuroprotective and anti-inflammatory effects. |
| M4526 | Benzoylpaeoniflorin | Benzoylpaeoniflorin, a natural compound extracted from paeonia lactiflora, has the potential to be used in the study of coronary heart disease by reducing apoptosis. |
| M4525 | Alibiflorin | Albiflorin, a monoterpenoid glycoside with neuroprotective effects, is the main component of peony root. Albiflorin also has anti-inflammatory, antioxidant and pain relieving effects. |
| M4524 | Ligustroflavone | Ligustroflavone, which can be extracted from Ligustrum lucidum, is a potential calcium sensitive receptor (CaSR) antagonist. Ligustroflavone has protective effect on diabetic osteoporosis mice. |
| M4523 | Specnuezhenide | Specnuezhenide ((8E)-Nuezhenide) was separated from the fruit of the ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) inhibited IL-1β -induced chondrocyte inflammation by inhibiting NF-κB and WNT /β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) showed anti-inflammatory effects in rat models of osteoarthritis (OA). |
| M4522 | Ursolic acid | Ursolic acid (Prunol) is a natural triterpenoid carboxylic acid compound with preventive and anticancer activities. Ursolic acid also has proteasome agonist activity, EC50=14 μmol/L. |
| M4521 | Dehydrocorydaline | Dehydrocorydaline is an alkaloid, it can regulate protein expression of Bax, Bcl-2. Dehydrocorydaline elevates p38 MAPK activation. Dehydrocorydaline elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline shows strong anti-malarial effects, and low cytotoxicity. |
| M4520 | (+)-Corydaline | Corydaline ((+) -corydaline) is an isoquinoline alkaloid extracted from Corydalis Yanhusuo. It is an inhibitor of AChE with IC50 of 226 µM. Corydaline is a μ-opioid receptor agonist (Ki = 1.23 µM) that inhibits the replication of enterovirus 71 (EV71) (IC50 = 25.23 µM). Corydaline has anti-angiogenesis, anti-allergy, gastric emptying and anti-nociception effects. |
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