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Cat. No. M4499
Crocin-I Structure
Size Price Availability Quantity
20mg USD 100  USD100 In stock
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Quality Control & Documentation
Biological Activity

Crocin I (Crocin I) is a nutritional supplement isolated from the stigmas of Crocus sativus. It has anti-inflammatory, anticancer, antidepressant and anticonvulsant effects.

Chemical Information
Molecular Weight 976.96
Formula C44H64O24
CAS Number 42553-65-1
Solubility (25°C) DMSO 100 mg/mL
Storage 2-8°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Reyhaneh Naderi, et al. Preparation and evaluation of crocin loaded in nanoniosomes and their effects on ischemia-reperfusion injuries in rat kidney

[2] Qingfeng Xiao, et al. Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress

[3] Ye Qiu, et al. The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice

[4] Qingfeng Xiao, et al. Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone in mice

[5] Xiaoxian Xie, et al. Crocin-I ameliorates the disruption of lipid metabolism and dysbiosis of the gut microbiota induced by chronic corticosterone in mice

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Tryptophol (Indole-3-ethanol) is an endogenous metabolite.


DL-Tryptophan is an endogenous metabolite.

Tricosanoic acid

Tricosanoic acid is a long-chain fatty acid and shown to be a hair growth stimulant.

Tiglic acid

Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite.

Abmole Inhibitor Catalog

Keywords: Crocin-I supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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