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2,3,5,4-tetrahydroxyl-diphenylethylene-2-o-glucoside

Cat. No. M4444
2,3,5,4-tetrahydroxyl-diphenylethylene-2-o-glucoside Structure
Synonym:

2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside

Size Price Availability Quantity
20mg USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

2,3,4', 5-Tetrahydroxystilbene 2-O-D-glucoside was isolated from the roots of polygonum species and inhibited the formation of 5-Hete, HHT and Thromboxane B2.

Chemical Information
Molecular Weight 406.38
Formula C20H22O9
CAS Number 82373-94-2
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Zeyuan Liu, et al. How to apply O 3 and PM 2.5 collaborative control to practical management in China: A study based on meta-analysis and machine learning

[2] No authors listed. Carteolol

[3] No authors listed. Iothalamate

[4] No authors listed. Clonazepam

[5] No authors listed. Amiodarone

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Keywords: 2,3,5,4-tetrahydroxyl-diphenylethylene-2-o-glucoside, 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside supplier, inhibitors, activators


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